PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12202948-2	2002	Studies using mostly ex vivo systems suggested diphenylamine-2-carboxylate (DPC), 5-nitro-2-(3-phenylpropylamino) benzoic acid (NPPB) and glybenclamide inhibit CFTR Cl- conductance (CFTR GCl).	5-nitro-2-(3-phenylpropylamino)benzoic acid	82-126	CF transmembrane conductance regulator	Homo sapiens	160-164	
12202948-2	2002	Studies using mostly ex vivo systems suggested diphenylamine-2-carboxylate (DPC), 5-nitro-2-(3-phenylpropylamino) benzoic acid (NPPB) and glybenclamide inhibit CFTR Cl- conductance (CFTR GCl).	5-nitro-2-(3-phenylpropylamino)benzoic acid	82-126	CF transmembrane conductance regulator	Homo sapiens	182-186	
12202948-8	2002	At a concentration of 10(-4) M, NPPB, DPC, glybenclamide, and DIDS were equipotent and blocked approximately 50% of irreversibly phosphorylated and ATP-activated CFTR GCl (DIDS = 49 +/- 10% > NPPB = 46 +/- 10% > DPC = 38 +/- 7% > glybenclamide = 34 +/- 5%; values are mean +/- SE expressed as % inhibition from the control).	5-nitro-2-(3-phenylpropylamino)benzoic acid	32-36	CF transmembrane conductance regulator	Homo sapiens	162-166	
25267914-6	2014	The practical utility of 5-nitro-2-(3-phenylpropylamino)benzoate (NPPB), one of the most efficacious potentiators of DeltaF508 CFTR identified to date, is limited by its pore-blocking side effect.	5-nitro-2-(3-phenylpropylamino)benzoic acid	66-70	CF transmembrane conductance regulator	Homo sapiens	127-131	
10516209-8	1999	When bronchi were pretreated with glibenclamide or 5-nitro-2-(3-phenylpropylamino)benzoic acid (both inhibitors of CFTR), the rate of ACh-induced liquid secretion was significantly reduced by 39 and 91%, respectively, compared with controls.	5-nitro-2-(3-phenylpropylamino)benzoic acid	51-94	CF transmembrane conductance regulator	Homo sapiens	115-119	
9218222-7	1997	5-Nitro-2(3-phenylpropylamino)-benzoate (NPPB) a blocker of the CF transmembrane conductance regulator (CFTR), converted secretion to absorption.	5-nitro-2-(3-phenylpropylamino)benzoic acid	41-45	CF transmembrane conductance regulator	Homo sapiens	64-102	
9218222-7	1997	5-Nitro-2(3-phenylpropylamino)-benzoate (NPPB) a blocker of the CF transmembrane conductance regulator (CFTR), converted secretion to absorption.	5-nitro-2-(3-phenylpropylamino)benzoic acid	41-45	CF transmembrane conductance regulator	Homo sapiens	104-108	
27413118-3	2016	Recently the chloride channel blocker and CFTR potentiator 5-nitro-2-(3-phenylpropylamino) benzoate (NPPB) has been reported to enhance CFTR activity by a mechanism that exploits the ATP hydrolysis-driven, nonequilibrium gating mechanism unique to CFTR.	5-nitro-2-(3-phenylpropylamino)benzoic acid	101-105	CF transmembrane conductance regulator	Homo sapiens	42-46	
27413118-3	2016	Recently the chloride channel blocker and CFTR potentiator 5-nitro-2-(3-phenylpropylamino) benzoate (NPPB) has been reported to enhance CFTR activity by a mechanism that exploits the ATP hydrolysis-driven, nonequilibrium gating mechanism unique to CFTR.	5-nitro-2-(3-phenylpropylamino)benzoic acid	101-105	CF transmembrane conductance regulator	Homo sapiens	136-140	
27413118-3	2016	Recently the chloride channel blocker and CFTR potentiator 5-nitro-2-(3-phenylpropylamino) benzoate (NPPB) has been reported to enhance CFTR activity by a mechanism that exploits the ATP hydrolysis-driven, nonequilibrium gating mechanism unique to CFTR.	5-nitro-2-(3-phenylpropylamino)benzoic acid	101-105	CF transmembrane conductance regulator	Homo sapiens	136-140	
15925323-2	2005	We estimated CFTR Cl(-) channel activity and transcellular Cl(-) secretion by measuring 5-nitro 2-(3-phenylpropylamino)benzoate (NPPB, a blocker of CFTR Cl(-) channel)-sensitive transepithelial conductance (Gt) and short-circuit current (Isc), respectively.	5-nitro-2-(3-phenylpropylamino)benzoic acid	129-133	CF transmembrane conductance regulator	Homo sapiens	148-152