PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8333852-0	1993	Suramin, an experimental chemotherapeutic drug, irreversibly blocks T cell CD45-protein tyrosine phosphatase in vitro.	Suramin	0-7	protein tyrosine phosphatase receptor type C	Homo sapiens	75-79	
8333852-5	1993	Here we demonstrate that suramin strongly inhibits the activity of CD45, the principal tyrosine specific protein phosphatase of T lymphocytes.	Suramin	25-32	protein tyrosine phosphatase receptor type C	Homo sapiens	67-71	
8333852-6	1993	Suramin-induced inactivation of CD45 is noncompetitive, irreversible and complete within 10 min.	Suramin	0-7	protein tyrosine phosphatase receptor type C	Homo sapiens	32-36	
8333852-7	1993	The ability of suramin to block CD45 mediated phosphatase function provides both new insight into the mechanism of action of this agent and a useful new probe for studies of T cell activation.	Suramin	15-22	protein tyrosine phosphatase receptor type C	Homo sapiens	32-36