PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9037251-2 1997 Compound A elicited a Type II difference spectrum and inhibited the Type I deoxycorticosterone (DOC) induced difference spectrum of sheep adrenal cytochrome P450c11 in a manner similar to that of S2, a biologically active fraction isolated from S. tuberculatiformis. Desoxycorticosterone 75-94 cytochrome P450, family 11, subfamily b, polypeptide 1 Rattus norvegicus 146-164 9037251-2 1997 Compound A elicited a Type II difference spectrum and inhibited the Type I deoxycorticosterone (DOC) induced difference spectrum of sheep adrenal cytochrome P450c11 in a manner similar to that of S2, a biologically active fraction isolated from S. tuberculatiformis. Desoxycorticosterone 96-99 cytochrome P450, family 11, subfamily b, polypeptide 1 Rattus norvegicus 146-164 8274438-3 1993 CYP11B1 is found in all the zones of the gland and catalyzes a single hydroxylation of deoxycorticosterone (DOC) in the 11 beta- or the 18-position. Desoxycorticosterone 87-106 cytochrome P450, family 11, subfamily b, polypeptide 1 Rattus norvegicus 0-7 7829497-2 1995 One of these (CYP11B1) encodes P450c11 beta, which is the steroid 11 beta-hydroxylase found solely in the adrenal zona fasciculata/reticularis, and is responsible for the conversion of 11-deoxycorticosterone to corticosterone. Desoxycorticosterone 185-207 cytochrome P450, family 11, subfamily b, polypeptide 1 Rattus norvegicus 14-21 7829497-2 1995 One of these (CYP11B1) encodes P450c11 beta, which is the steroid 11 beta-hydroxylase found solely in the adrenal zona fasciculata/reticularis, and is responsible for the conversion of 11-deoxycorticosterone to corticosterone. Desoxycorticosterone 185-207 cytochrome P450, family 11, subfamily b, polypeptide 1 Rattus norvegicus 31-38 7829497-12 1995 Transfection of eukaryotic cells with a vector expressing P450c11B3 shows that this form of P450c11 can convert 11-deoxycorticosterone (DOC) to corticosterone and thus has the same enzymatic activity as P450c11 beta. Desoxycorticosterone 112-134 cytochrome P450, family 11, subfamily b, polypeptide 1 Rattus norvegicus 58-65 7829497-12 1995 Transfection of eukaryotic cells with a vector expressing P450c11B3 shows that this form of P450c11 can convert 11-deoxycorticosterone (DOC) to corticosterone and thus has the same enzymatic activity as P450c11 beta. Desoxycorticosterone 112-134 cytochrome P450, family 11, subfamily b, polypeptide 1 Rattus norvegicus 92-99 7829497-12 1995 Transfection of eukaryotic cells with a vector expressing P450c11B3 shows that this form of P450c11 can convert 11-deoxycorticosterone (DOC) to corticosterone and thus has the same enzymatic activity as P450c11 beta. Desoxycorticosterone 136-139 cytochrome P450, family 11, subfamily b, polypeptide 1 Rattus norvegicus 58-65 7829497-12 1995 Transfection of eukaryotic cells with a vector expressing P450c11B3 shows that this form of P450c11 can convert 11-deoxycorticosterone (DOC) to corticosterone and thus has the same enzymatic activity as P450c11 beta. Desoxycorticosterone 136-139 cytochrome P450, family 11, subfamily b, polypeptide 1 Rattus norvegicus 92-99 8123004-2 1994 The classical rat 11 beta-hydroxylase or CYP11B1 enzyme hydroxylates deoxycorticosterone to corticosterone and 18-hydroxydeoxycorticosterone and is located throughout the adrenal. Desoxycorticosterone 69-88 cytochrome P450, family 11, subfamily b, polypeptide 1 Rattus norvegicus 41-48 8274438-3 1993 CYP11B1 is found in all the zones of the gland and catalyzes a single hydroxylation of deoxycorticosterone (DOC) in the 11 beta- or the 18-position. Desoxycorticosterone 108-111 cytochrome P450, family 11, subfamily b, polypeptide 1 Rattus norvegicus 0-7 1597135-4 1992 In contrast, the product of CYP11B1 (11 beta-hydroxylase) mediates only the 11 beta-hydroxylation of deoxycorticosterone and 11-deoxycortisol. Desoxycorticosterone 101-120 cytochrome P450, family 11, subfamily b, polypeptide 1 Rattus norvegicus 28-35 8473350-4 1993 When the two cDNAs were expressed in COS-7 cells and steroid conversion rates of the transformed cells were determined, a ratio of 18-hydroxylation to 11 beta-hydroxylation of 11-deoxycorticosterone by P450(11 beta)-DS-expressed cells was 0.58, whereas that by P450(11 beta)-DR-expressed cells was 0.23. Desoxycorticosterone 176-198 cytochrome P450, family 11, subfamily b, polypeptide 1 Rattus norvegicus 202-218 2052554-2 1991 P450c11 converts deoxycorticosterone to corticosterone and aldosterone, and P450scc converts cholesterol to pregnenolone. Desoxycorticosterone 17-36 cytochrome P450, family 11, subfamily b, polypeptide 1 Rattus norvegicus 0-7 2788699-7 1989 The present findings suggest that decreased expression of steroid 11 beta-hydroxylase could contribute to the increased secretion of 11-deoxycorticosterone during the early stages of adrenal regeneration. Desoxycorticosterone 133-155 cytochrome P450, family 11, subfamily b, polypeptide 1 Rattus norvegicus 58-85 26610754-10 2016 The changes in the adrenal gland and plasma concentration of steroids were thought to reflect inhibited metabolism of deoxycorticosterone to corticosterone through inhibition of CYP11B1, and compensatory reaction for the inhibition. Desoxycorticosterone 118-137 cytochrome P450, family 11, subfamily b, polypeptide 1 Rattus norvegicus 178-185