PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24580729-6	2014	The substrate (progesterone) and the product (deoxycorticosterone) of 21-hydroxylase are substrates of 20alpha-HSD, thus 20alpha-HSD (Akr1c18) gene expression was investigated.	Desoxycorticosterone	46-65	cytochrome P450, family 21, subfamily a, polypeptide 1	Mus musculus	70-84	
27432820-7	2016	In vitro assays demonstrated that Cyp21a1-expressing fibroblasts can uptake progesterone from the culture media, convert it to deoxycorticosterone (DOC), and subsequently release DOC back into the media.	Desoxycorticosterone	127-146	cytochrome P450, family 21, subfamily a, polypeptide 1	Mus musculus	34-41	
27432820-7	2016	In vitro assays demonstrated that Cyp21a1-expressing fibroblasts can uptake progesterone from the culture media, convert it to deoxycorticosterone (DOC), and subsequently release DOC back into the media.	Desoxycorticosterone	148-151	cytochrome P450, family 21, subfamily a, polypeptide 1	Mus musculus	34-41	
27432820-7	2016	In vitro assays demonstrated that Cyp21a1-expressing fibroblasts can uptake progesterone from the culture media, convert it to deoxycorticosterone (DOC), and subsequently release DOC back into the media.	Desoxycorticosterone	179-182	cytochrome P450, family 21, subfamily a, polypeptide 1	Mus musculus	34-41	
27432820-8	2016	Autotransplantation of Cyp21a1-expressing fibroblasts into the subcutaneous tissues of the back resulted in a significant reduction in the serum progesterone/DOC ratio in four of six 21-OHD mice at 4 weeks after injection.	Desoxycorticosterone	158-161	cytochrome P450, family 21, subfamily a, polypeptide 1	Mus musculus	23-30	
7925109-4	1994	21-OHase catalyzes the conversion of progesterone to deoxycorticosterone during adrenal steroidogenesis in mice; therefore, H-2aw18 homozygous mice are unable to synthesize corticosteroids.	Desoxycorticosterone	53-72	cytochrome P450, family 21, subfamily a, polypeptide 1	Mus musculus	0-8	
24580729-11	2014	CONCLUSION: Progesterone is present at high levels during gestation and the product of 21-hydroxylase, deoxycorticosterone, can bind the glucocorticoid receptor with an affinity close to that of corticosterone.	Desoxycorticosterone	103-122	cytochrome P450, family 21, subfamily a, polypeptide 1	Mus musculus	87-101