PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23116186-0 2012 Design and optimization of pyrazinecarboxamide-based inhibitors of diacylglycerol acyltransferase 1 (DGAT1) leading to a clinical candidate dimethylpyrazinecarboxamide phenylcyclohexylacetic acid (AZD7687). Pyrazinamide 27-46 diacylglycerol O-acyltransferase 1 Homo sapiens 67-99 23116186-0 2012 Design and optimization of pyrazinecarboxamide-based inhibitors of diacylglycerol acyltransferase 1 (DGAT1) leading to a clinical candidate dimethylpyrazinecarboxamide phenylcyclohexylacetic acid (AZD7687). Pyrazinamide 27-46 diacylglycerol O-acyltransferase 1 Homo sapiens 101-106 23116186-1 2012 A new series of pyrazinecarboxamide DGAT1 inhibitors was designed to address the need for a candidate drug with good potency, selectivity, and physical and DMPK properties combined with a low predicted dose in man. Pyrazinamide 16-35 diacylglycerol O-acyltransferase 1 Homo sapiens 36-41