PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11301070-2 2001 Whether corticosterone plays a role in the clozapine-induced Fos response is the subject of this study. Corticosterone 8-22 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 61-64 11301070-6 2001 Implantation of the corticosterone pellet in both sham-operated and adrenalectomized animals, reduced the clozapine-induced Fos responses strongly in the hypothalamic paraventricular nucleus, the subfornical organ and possibly in the prefrontal cortex; in the supraoptic nucleus, this effect was seen only in intact animals. Corticosterone 20-34 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 124-127 11719001-25 2001 Rats receiving low dose corticosterone showed increased Fos-b expression following 9 days stress in the lateral septum and in the dorsal and medial parts of the paraventricular nucleus compared to either control, stressed rats or those receiving the higher corticosterone dose and repeated stress. Corticosterone 24-38 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 56-59 9548700-4 1998 Rats with constant corticosterone levels displayed enhanced footshock-induced Fos expression in the parvicellular compartment of the PVH, as well as in certain limbic and somatosensory cell groups, the locus coeruleus, but not in medullary catecholaminergic cell groups. Corticosterone 19-33 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 78-81 9483552-6 1998 Fos immunoreactivity was marked in parvocellular regions of the paraventricular nucleus of the hypothalamus following both restraint periods and at both ages, an observation consistent with previous observations that restraint increases plasma corticosterone at both ages. Corticosterone 244-258 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 0-3 9436645-5 1997 We further show that prior exposure to IMO stress for 6 days, or implantation of corticosterone pellets suppresses the induction of c-fos, fos B, jun B and NGFI-B, but not that of NGFI-A in the rat PVH. Corticosterone 81-95 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 132-137 9117393-4 1996 Stress-induced levels of corticosterone were significantly lower in late pregnant and early lactating rats compared with the levels in virgin females, and this correlated with a marked attenuation of stress-induced c-fos mRNA expression in the parvocellular division of the PVN. Corticosterone 25-39 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 215-220 8938747-7 1996 A significant positive correlation was found between the number of Fos-positive nuclei in the central or basolateral nucleus of the amygdala and the serum corticosterone concentration. Corticosterone 155-169 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 67-70 8938747-9 1996 Our findings indicate that the central role of neurotensin in increasing serum corticosterone involves the induction of Fos in the central and basolateral nuclei of the amygdala. Corticosterone 79-93 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 120-123 8950098-8 1996 Moreover, a significant correlation existed between the number of Fos-ir neurons in the PVN and the plasma corticosterone level. Corticosterone 107-121 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 66-69 8720501-3 1996 To this end, stress-induced c-fos expression was characterized in adrenalectomized (ADX) or adrenalectomized and corticosterone replaced (ADX/B) male rats. Corticosterone 113-127 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 28-33 8563722-0 1995 Bacterial lipopolysaccharide-induced changes in FOS protein expression in the rat brain: correlation with thermoregulatory changes and plasma corticosterone. Corticosterone 142-156 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 48-51 8563722-1 1995 In the present study the regions of the brain showing an increase in the number of FOS protein stained cells 180 min following intravenous saline or bacterial lipopolysaccharide (LPS) treatment were investigated and correlated with changes in body temperature and plasma corticosterone levels. Corticosterone 271-285 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 83-86 8563722-9 1995 Plasma corticosterone was unaffected by the lowest dose of LPS (0.35 micrograms), however the higher doses employed (3.5 and 50 micrograms) caused significant increases in plasma corticosterone which correlated with the increases in the number of FOS stained cells in the pPVN. Corticosterone 179-193 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 247-250 7651620-3 1995 Adrenalectomized rats displayed an enhanced number of Fos-positive neurons within the caudal-most portions of trigeminal subnucleus caudalis compared to that seen in adrenal-intact animals, an effect reversed by a single acute injection of corticosterone (1 mg/kg, i.p.) Corticosterone 240-254 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 54-57 8332263-10 1993 The appearance of Fos-like immunoreactivity within caudal portions of the nucleus was increased only by noxious intensities of stimulation and was further enhanced in animals with low levels of corticosterone. Corticosterone 194-208 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 18-21 1488127-12 1992 There was a marked correlation between the number of c-fos-positive neurons in the supraoptic nucleus or paraventricular nucleus and plasma levels of corticosterone 60 min after infusion, but not with arginine-vasopressin levels. Corticosterone 150-164 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 53-58 1465198-13 1992 Corticosterone levels were raised by both stress and corticotropin-releasing factor, but pretreatment with alpha-helical corticotropin-releasing factor reduced them after either procedure, which correlates with c-fos expression in the paraventricular nucleus and ventrolateral septum. Corticosterone 0-14 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 211-216 1511271-4 1992 Both unconditioned and conditioned stressors increased c-fos mRNA levels in the locus ceruleus which correlated with stress-induced plasma corticosterone concentrations. Corticosterone 139-153 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 55-60 32574519-0 2020 Changes in c-fos and p-CREB signaling following exposure to forced swim stress or exogenous corticosterone during morphine-induced place preference are dependent on glucocorticoid receptor in the basolateral amygdala. Corticosterone 92-106 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 11-16 32574519-6 2020 In the PFC, in addition to FSS, corticosterone could raise c-fos expression, which was blocked by RU38486. Corticosterone 32-46 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 59-64 32512137-5 2020 Furthermore, corticosterone administration into male rats as a rodent model of depression induced significantly higher c-Fos expression in 5-HT3AR-positive GABAergic neurons compared to that in 5-HT neurons within the DRN. Corticosterone 13-27 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 119-124 26297864-9 2015 Corticosterone decreased maternal care, plasma oxytocin levels, milk consumption by the pups, the activation of oxytocinergic neurons in hypothalamic nuclei, and c-Fos immunoreactivity in MPOA neurons. Corticosterone 0-14 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 162-167 24829502-2 2014 We hypothesized that elevated corticosterone (Cort) within the dorsal hindbrain (DHB) would: 1) enhance arterial pressure and neuroendocrine responses to novel and repeated restraint stress, 2) increase c-Fos expression in regions of the brain involved in sympathetic stimulation during stress, and 3) recruit a vasopressin-mediated blood pressure response to acute stress. Corticosterone 30-44 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 203-208 24845185-7 2014 Following CVS, basal and 15 min post-restraint plasma corticosterone levels were increased by NTS GR antagonism, which was associated with an increase in Fos immunoreactivity within the PVN. Corticosterone 54-68 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 154-157 23806722-13 2013 bLRs" increase in positive affect after chronic EC was coupled with significant positive correlations between corticosterone levels and c-fos mRNA in the accumbens. Corticosterone 110-124 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 136-141 23806722-14 2013 Conversely, a decline in the rate of positive calls in bHRs after chronic EC was associated with a negative correlation between corticosterone and accumbens c-fos mRNA. Corticosterone 128-142 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 157-162 23098799-0 2013 Effects of chronic treatment with corticosterone and imipramine on fos immunoreactivity and adult hippocampal neurogenesis. Corticosterone 34-48 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 67-70 21185871-8 2011 Importantly, the increase of corticosterone level after escape or panic-like response was paralleled by an increase of neuronal activation of c-Fos in both the parvocellular and magnocellular paraventricular nucleus of the hypothalamus. Corticosterone 29-43 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 142-147 19100597-0 2010 Single-dose and chronic corticosterone treatment alters c-Fos or FosB immunoreactivity in the rat cerebral cortex. Corticosterone 24-38 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 56-61 19100597-1 2010 The aim of this study was to examine the effects of single-dose and chronic corticosterone treatment on the inducible transcription factor c-Fos and FosB, and thereby to estimate the effects of high-doses of corticosterone on calcium-dependent neuronal responses in the rat cerebral cortex. Corticosterone 76-90 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 139-144 19100597-10 2010 It was found that a single-dose administration of corticosterone resulted in a significant, time-dependent increase of c-Fos protein immunoreactivity in the granule cell layer of the dentate gyrus, as well as in regions CA1 and CA3 of the hippocampus 12 and 24h post-injection with respect to control animals. Corticosterone 50-64 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 119-124 19100597-18 2010 The present data suggest that single-dose corticosterone treatment increases immunoreactivity of c-Fos protein in a time-dependent manner, 12 and 24h post-injection in the rat hippocampus and the neocortex, whereas chronic corticosterone treatment influences FosB immunoreactivity, primarily in the dentate gyrus. Corticosterone 42-56 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 97-102 19778539-5 2009 Fos/OT neurons in the posterior parvocellular subdivision of the PVN were increased after refeeding, with a higher number in the ADX group, compared with sham and ADX+corticosterone (B) groups, with no difference in the medial parvocellular and magnocellular subdivisions of the PVN. Corticosterone 167-181 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 0-3 19460425-9 2009 Furthermore, in males and females, the c-Fos response of npEW-Ucn1 neurons upon restraint stress was blunted in animals with MS history, a phenomenon that was concomitant with dampening of the HPA corticosterone response in females but not in males. Corticosterone 197-211 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 39-44 18485334-6 2008 In the hippocampus, a single corticosterone dose (10 mg/kg, s.c.) caused a widespread and transient reduction of fosB mRNA after 0.8 h, whereas changes in both c-fos and fra-1 mRNA levels were restricted to the dentate gyrus region. Corticosterone 29-43 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 160-165 17594906-0 2007 The effects of acute corticosterone administration on anxiety, endogenous corticosterone, and c-Fos expression in the rat brain. Corticosterone 21-35 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 94-99 17462630-0 2007 Central neural distribution of immunoreactive Fos and CRH in relation to plasma ACTH and corticosterone during sepsis in the rat. Corticosterone 89-103 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 46-49 17462630-6 2007 The number of Fos-positive cell nuclei in the NTS on D3 and D4 did not differ but had greater variance on D3 than on D4 (P<0.01) with a divergent response in the PM of D3 that was correlated with plasma ACTH (r=0.927, P<0.01) but not with corticosterone. Corticosterone 245-259 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 14-17 17107707-5 2006 On the other hand, repeated administration of corticosterone (for 25 days, the final injection 90 min before contextual fear conditioning training) decreased plasma corticosterone concentration, inhibited exploratory behavior, enhanced freezing responses on retest and produced a complex pattern of changes in c-Fos expression, stimulated by exposure of rats to the aversively conditioned context. Corticosterone 46-60 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 310-315 16150912-9 2005 c-fos mRNA responses in the anterior pituitary followed those in PVN and reflect central drive of the HPA axis even if corticosterone responses are strongly reduced. Corticosterone 119-133 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 0-5 15667452-1 2004 We examined the extent to which basal levels of corticosterone, which vary in a circadian fashion, influence the pattern of Fos protein expression in the paraventricular nucleus of the hypothalamus (PVN), the hippocampal formation and three different functional cortical areas. Corticosterone 48-62 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 124-127 15667452-9 2004 Corticosterone replacement normalized the adrenalectomy effect on Fos expression in both brain regions. Corticosterone 0-14 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 66-69 12865328-6 2003 Pretreatment with corticosterone decreased the number of Fos-immunoreactive cells in the PVN and SON but not in the DMH. Corticosterone 18-32 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 57-60 12853419-0 2003 c-fos reduces corticosterone-mediated effects on neurotrophic factor expression in the rat hippocampal CA1 region. Corticosterone 14-28 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 0-5 12506852-2 2002 We demonstrated previously that a long-duration restraint stress (RTS) evoked adaptive change, characterized by transient increase and gradual recovery to basal level in c-fos mRNA/c-fos protein (Fos) expression in the hypothalamic paraventricular nucleus (PVN) and in plasma adrenocorticotropin (ACTH) levels, although circulating corticosterone (CORT) remained at a high level. Corticosterone 332-346 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 170-175 12506852-2 2002 We demonstrated previously that a long-duration restraint stress (RTS) evoked adaptive change, characterized by transient increase and gradual recovery to basal level in c-fos mRNA/c-fos protein (Fos) expression in the hypothalamic paraventricular nucleus (PVN) and in plasma adrenocorticotropin (ACTH) levels, although circulating corticosterone (CORT) remained at a high level. Corticosterone 332-346 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 196-199 12217933-10 2002 These data also provide further evidence for a dissociation between the activation of c-fos and corticotrophin-releasing factor (CRF) mRNA in the PVN, as we have previously demonstrated that this dose of cyanamide alone is sufficient to evoke a sustained increase in plasma corticosterone and an increase in CRF mRNA. Corticosterone 274-288 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 86-91