PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11994423-5	2002	The possible roles of DSBs in relation to AID function and SHM are discussed.	dsbs	22-26	activation induced cytidine deaminase	Homo sapiens	42-45	
21383964-6	2011	AID-induced translocations were strongly enhanced in yeast THO null mutants, consistent with the idea that AID-mediated DSBs depend on R-loop formation.	dsbs	120-124	activation induced cytidine deaminase	Homo sapiens	0-3	
21383964-6	2011	AID-induced translocations were strongly enhanced in yeast THO null mutants, consistent with the idea that AID-mediated DSBs depend on R-loop formation.	dsbs	120-124	activation induced cytidine deaminase	Homo sapiens	107-110	
30946744-2	2019	Joining of AID-dependent DSBs within IGH facilitate CSR and effective humoral immunity, but ligation to DSBs in non-IGH chromosomes leads to chromosomal translocations.	dsbs	25-29	activation induced cytidine deaminase	Homo sapiens	11-14	
30946744-3	2019	Thus, the mechanism by which AID-dependent DSBs are repaired requires careful examination.	dsbs	43-47	activation induced cytidine deaminase	Homo sapiens	29-32	
28933967-2	2018	AID is responsible for producing high-affinity and high-specificity antibodies against an infectious agent, through the physiological DNA alteration processes of antibody genes by somatic hypermutation (SHM) and class-switch recombination (CSR) and functions by deaminating deoxycytidines (dC) to deoxyuridines (dU), thereby introducing point mutations and double-stranded chromosomal breaks (DSBs).	dsbs	393-397	activation induced cytidine deaminase	Homo sapiens	0-3	
23181381-3	2013	AID displays a mutagenic activity by catalyzing targeted deamination of deoxycytidine (dC) residues in DNA resulting in dU:dG mismatches, which are processed into point-mutations in SHM or double-strand breaks (DSBs) in CSR.	dsbs	211-215	activation induced cytidine deaminase	Homo sapiens	0-3	
27777312-2	2017	The introduction of DSBs is initiated by activation-induced cytidine deaminase (AID) and requires base excision repair (BER) and mismatch repair (MMR).	dsbs	20-24	activation induced cytidine deaminase	Homo sapiens	41-78	
27777312-2	2017	The introduction of DSBs is initiated by activation-induced cytidine deaminase (AID) and requires base excision repair (BER) and mismatch repair (MMR).	dsbs	20-24	activation induced cytidine deaminase	Homo sapiens	80-83	
24528169-3	2014	Endogenous sources of DSBs leading to translocations include inappropriate recombination activating gene (RAG) or activation-induced deaminase (AID) activity during immune receptor maturation.	dsbs	22-26	activation induced cytidine deaminase	Homo sapiens	114-142	
24528169-3	2014	Endogenous sources of DSBs leading to translocations include inappropriate recombination activating gene (RAG) or activation-induced deaminase (AID) activity during immune receptor maturation.	dsbs	22-26	activation induced cytidine deaminase	Homo sapiens	144-147	
22826323-10	2012	Our results reveal novel cell cycle dynamics in response to AID-initiated DSBs, and suggest that the regulation of the repair of these DSBs through the cell cycle may ensure proper class switching while preventing AID-induced genomic instability.	dsbs	74-78	activation induced cytidine deaminase	Homo sapiens	60-63	
22826323-10	2012	Our results reveal novel cell cycle dynamics in response to AID-initiated DSBs, and suggest that the regulation of the repair of these DSBs through the cell cycle may ensure proper class switching while preventing AID-induced genomic instability.	dsbs	74-78	activation induced cytidine deaminase	Homo sapiens	214-217