PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25948581-5	2015	These results suggest that in addition to drive cell cycle progression, CDK also targets RNF4, which is involved in the regulatory network of DSBs repair.	dsbs	142-146	ring finger protein 4	Homo sapiens	89-93	
33408245-5	2021	Thus, our data show that PARylation differentially regulates SUMO-dependent recruitment of ataxin-3 and RNF4 to DSBs, explaining how both proteins can play a stimulatory role at DSBs despite their opposing activities.	dsbs	112-116	ring finger protein 4	Homo sapiens	104-108	
33408245-5	2021	Thus, our data show that PARylation differentially regulates SUMO-dependent recruitment of ataxin-3 and RNF4 to DSBs, explaining how both proteins can play a stimulatory role at DSBs despite their opposing activities.	dsbs	178-182	ring finger protein 4	Homo sapiens	104-108	
24142876-6	2013	Notably, RNF4 repression substantially suppressed the accumulation of DSBs in ATR-deficient cells, and this decrease in breaks was enhanced by concomitant inhibition of PLK1.	dsbs	70-74	ring finger protein 4	Homo sapiens	9-13	
22661229-2	2012	Here, we show that human RNF4, a small ubiquitin-like modifier (SUMO)-targeted ubiquitin E3 ligase, is recruited to DSBs in a manner requiring its SUMO interaction motifs, the SUMO E3 ligases PIAS1 and PIAS4, and various DSB-responsive proteins.	dsbs	116-120	ring finger protein 4	Homo sapiens	25-29