PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31795137-4 2019 The Ku heterodimer formed by Ku70 and Ku80 recognizes DSBs and facilitates the recruitment of accessory factors (e.g., DNA-PKcs, Artemis, Paxx and Mri/Cyren) and downstream core factor subunits X-ray repair cross-complementing group 4 (XRCC4), XRCC4-like factor (XLF), and DNA ligase 4 (Lig4). dsbs 54-58 X-ray repair complementing defective repair in Chinese hamster cells 6 Mus musculus 29-33 28759779-2 2017 C-NHEJ includes the core Ku70 and Ku80 (or Ku86) heterodimer that binds DSBs and thus promotes recruitment of accessory downstream NHEJ factors XLF, PAXX, DNA-PKcs, Artemis and other core subunits, XRCC4 and DNA Ligase 4 (Lig4). dsbs 72-76 X-ray repair complementing defective repair in Chinese hamster cells 6 Mus musculus 25-29 26280532-3 2015 Using mouse cells containing targeted mutant alleles of Mre11 (Mre11a) and/or Ku70 (Xrcc6), together with pharmacologic kinase inhibition, we demonstrate that ATM can be activated by DSBs in the absence of MRN. dsbs 183-187 X-ray repair complementing defective repair in Chinese hamster cells 6 Mus musculus 78-82 26280532-3 2015 Using mouse cells containing targeted mutant alleles of Mre11 (Mre11a) and/or Ku70 (Xrcc6), together with pharmacologic kinase inhibition, we demonstrate that ATM can be activated by DSBs in the absence of MRN. dsbs 183-187 X-ray repair complementing defective repair in Chinese hamster cells 6 Mus musculus 84-89 23857907-10 2013 In summary, our data indicate that Ku70 is important for repairing DSBs in somatic cells and in late spermatocytes of the testis, thereby assuring the fidelity of spermatogenesis. dsbs 67-71 X-ray repair complementing defective repair in Chinese hamster cells 6 Mus musculus 35-39