PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29581593-2	2018	This recruitment is dependent on ubiquitylation of adjacent chromatin areas by E3 ubiquitin ligases such as RNF8 and RNF168, which are recruited sequentially to the DSBs.	dsbs	165-169	ring finger protein 8	Homo sapiens	108-112	
25955491-12	2015	As a result, a conclusion could be drawn that RNF8 recruits and ubiquitinates many factors to repair DNA damage, including DSBs, thereby conferring radioresistance to NPC cells.	dsbs	123-127	ring finger protein 8	Homo sapiens	46-50	
20876283-6	2010	Further, the destabilization of nucleosomes by p400 is required for the RNF8-dependent ubiquitination of chromatin, and for the subsequent recruitment of brca1 and 53BP1 to DSBs.	dsbs	173-177	ring finger protein 8	Homo sapiens	72-76	
20725033-3	2010	DSBs elicit a signalling cascade that modifies the chromatin surrounding the break, first by ATM-dependent phosphorylation and then by RNF8-, RNF168- and BRCA1-dependent regulatory ubiquitination.	dsbs	0-4	ring finger protein 8	Homo sapiens	135-139