PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22139836-8 2012 Overall, these findings suggest that Abeta mediates inhibition of the DNA-PK-dependent nonhomologous end joining pathway contributing to the accumulation of DSBs that, if not efficiently repaired, may lead to the neuronal loss observed in AD. dsbs 157-161 amyloid beta precursor protein Rattus norvegicus 37-42