PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21665351-6 2011 According to the structural information, this titration behavior appears to be the consequence of a conformational equilibrium that depends on the protonation of some Glu residues located at the C-terminal alpha3 helix and at the hairpin formed by strands beta2 and beta3. Glutamic Acid 167-170 basic helix-loop-helix family member e22 Homo sapiens 266-271