PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23093938-8 2012 However, conversion of these residues to the phosphomimetic glutamic acid restored histone binding suggesting that phosphorylation of serine 10 and threonine 14 may modulate LANA function. Glutamic Acid 60-73 LANA Human gammaherpesvirus 8 174-178 16861237-6 2006 From the results of binding assays, a region containing the Glu/Asp-rich domain within LANA, and a central region including the second paired amphipathic helix within Daxx contributed to the interaction. Glutamic Acid 60-63 LANA Human gammaherpesvirus 8 87-91 11533207-8 2001 Moreover, we demonstrated that specific domains of LANA containing the putative leucine zipper and the glutamic acid-rich region are highly effective in upregulating these viral promoters, while the amino-terminal region (435 amino acids) exhibited little or no transactivation activity in our assays. Glutamic Acid 103-116 LANA Human gammaherpesvirus 8 51-55 16879850-4 2006 RFHVMn LANA reacts with monoclonal antibodies specific for a glutamic acid-proline dipeptide motif and a glutamic acid-glutamine-rich motif in the KSHV LANA repeat region. Glutamic Acid 61-74 LANA Human gammaherpesvirus 8 7-11 26420481-6 2015 As expected, LANA mutants with alanine or glutamate substitutions in the central, peripheral, or lateral portions of the positive patch maintained the ability to bind DNA by EMSA. Glutamic Acid 42-51 LANA Human gammaherpesvirus 8 13-17