PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15758178-8 2005 Functionally, our data suggest that AMPA receptors complexed with stargazin (and possibly also with other TARPs) at the postsynaptic membrane are significantly more responsive to synaptically released glutamate compared with AMPA receptors lacking stargazin/TARP interaction. Glutamic Acid 201-210 TCR gamma alternate reading frame protein Homo sapiens 106-110 22211840-4 2012 Specifically, with AMPA receptors comprising gamma-2, the cerebellar-enriched TARP isoform, CNIH-2 decreases I(KA) /I(Glu) ratio and decreases cyclothiazide efficacy while having minimal impact on recovery from desensitization and deactivation kinetics. Glutamic Acid 118-121 TCR gamma alternate reading frame protein Homo sapiens 78-82 28768197-6 2017 Furthermore, the dual effects of TARPs can account for biphasic steady-state glutamate concentration-response curves-a phenomenon termed "autoinactivation," previously thought to reflect desensitization-mediated AMPAR/TARP dissociation. Glutamic Acid 77-86 TCR gamma alternate reading frame protein Homo sapiens 33-37 19146816-0 2009 Autoinactivation of neuronal AMPA receptors via glutamate-regulated TARP interaction. Glutamic Acid 48-57 TCR gamma alternate reading frame protein Homo sapiens 68-72 32994336-10 2020 Thus, isoform-specific differences in TARP modulation of recovery from desensitization influence receptor responses to repeated brief applications of glutamate, and these differences may impact frequency-dependent synaptic signaling in the mammalian central nervous system.Significance Statement:AMPA receptors are major determinants of excitatory synaptic strength. Glutamic Acid 150-159 TCR gamma alternate reading frame protein Homo sapiens 38-42 32994336-15 2020 We observed that the TARP isoforms and duration of glutamate application uniquely modulate time constants and the proportion of fast and slow components through a previously unidentified TARP domain. Glutamic Acid 51-60 TCR gamma alternate reading frame protein Homo sapiens 187-191