PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16839343-2	2006	Previously, we have demonstrated that region Glu(1811)-Lys(1818) within FVIII light chain constitutes an important binding region for this receptor.	Glutamic Acid	45-48	coagulation factor VIII	Homo sapiens	72-77	
12522143-9	2003	In line with this observation, LRP binding was inhibited by a recombinant antibody fragment that specifically binds to the FVIII sequence Glu(1811)-Lys(1818).	Glutamic Acid	138-141	coagulation factor VIII	Homo sapiens	123-128	
12522143-12	2003	This suggests that multiple sites in FVIII contribute to high-affinity LRP binding, one of which is the FVIII A3 domain region Glu(1811)-Lys(1818).	Glutamic Acid	127-130	coagulation factor VIII	Homo sapiens	37-42	
12522143-12	2003	This suggests that multiple sites in FVIII contribute to high-affinity LRP binding, one of which is the FVIII A3 domain region Glu(1811)-Lys(1818).	Glutamic Acid	127-130	coagulation factor VIII	Homo sapiens	104-109	
7974349-3	1994	The epitopes of MAbs 418 and 522, which inhibit the binding of vWF to Factor VIII (FVIII), were localized between Leu 2 and Arg 53 and between Glu 35 and Ile 81 of the vWF subunit respectively, within the N-terminal trypsin fragment called SpIII-T4 [amino acids (aa) 1-272] which contains a binding domain for FVIII.	Glutamic Acid	143-146	coagulation factor VIII	Homo sapiens	70-81	
7974349-3	1994	The epitopes of MAbs 418 and 522, which inhibit the binding of vWF to Factor VIII (FVIII), were localized between Leu 2 and Arg 53 and between Glu 35 and Ile 81 of the vWF subunit respectively, within the N-terminal trypsin fragment called SpIII-T4 [amino acids (aa) 1-272] which contains a binding domain for FVIII.	Glutamic Acid	143-146	coagulation factor VIII	Homo sapiens	83-88	
27126696-6	2016	We generated and employed a CHO-DG44 cell clone producing an rFVIII variant retaining a portion of the B-domain and the FVIII native cleavage site between Arg(1648) and Glu(1649).	Glutamic Acid	169-172	coagulation factor VIII	Homo sapiens	62-67	
14629468-3	2003	Results of these studies indicate that in the presence of FX (1.5 micro m), the enzyme (active-site-inhibited Glu-Gly-Arg-FIXa, EGR-FIXa) and procofactor (FVIII) bind to an equal number (approximately 700 sites/platelet) of receptors whereas the active cofactor (FVIIIa) binds an additional approximately 500 high-affinity FVIIIa binding sites per platelet (Kd approximately 0.8 nm).	Glutamic Acid	110-113	coagulation factor VIII	Homo sapiens	155-160	
3150544-2	1988	One of these new derivatives, FVIII delta II, in which amino acids 771(pro)-1666(asp) have been deleted, no longer contains the protease cleavage site at amino acid position 1648(arg)-1649(glu) known to be involved in the initial step of FVIII processing.	Glutamic Acid	189-192	coagulation factor VIII	Homo sapiens	30-35	
20735721-9	2010	FVIII bound to Glu-Gly-Arg-active-site-modified FVIIa (K(d), ~0.8 nM) with a higher affinity for the HCh than for the LCh (K(d), 5.9 and 18.9 nm).	Glutamic Acid	15-18	coagulation factor VIII	Homo sapiens	0-5