PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21346098-7	2011	At the cellular level, the HFE mutant protein resulting from the H63D HFE gene variant is associated with iron dyshomeostasis, increased oxidative stress, glutamate release, tau phosphorylation, and alteration in inflammatory response, each of which is under investigation as a contributing factor to neurodegenerative diseases.	Glutamic Acid	155-164	homeostatic iron regulator	Homo sapiens	27-30	
19560233-0	2011	HFE polymorphisms affect cellular glutamate regulation.	Glutamic Acid	34-43	homeostatic iron regulator	Homo sapiens	0-3	
19560233-5	2011	In support of this hypothesis, expression of H63D HFE is associated with increased calcium-induced glutamate secretion and decreased cellular glutamate uptake.	Glutamic Acid	99-108	homeostatic iron regulator	Homo sapiens	50-53	
19560233-5	2011	In support of this hypothesis, expression of H63D HFE is associated with increased calcium-induced glutamate secretion and decreased cellular glutamate uptake.	Glutamic Acid	142-151	homeostatic iron regulator	Homo sapiens	50-53	
19560233-8	2011	HFE-dependent effects on glutamate uptake were confirmed in astrocytoma cell lines with endogenous expression of HFE.	Glutamic Acid	25-34	homeostatic iron regulator	Homo sapiens	0-3	
19560233-8	2011	HFE-dependent effects on glutamate uptake were confirmed in astrocytoma cell lines with endogenous expression of HFE.	Glutamic Acid	25-34	homeostatic iron regulator	Homo sapiens	113-116	
19560233-9	2011	The ability of minocycline and the antioxidant Trolox to increase glutamate uptake differed by HFE genotype and implicate oxidative stress in glutamate regulation.	Glutamic Acid	66-75	homeostatic iron regulator	Homo sapiens	95-98	
19560233-10	2011	This study demonstrates HFE cellular effects that extend beyond iron regulation, and suggests that H63D HFE may promote glutamate toxicity.	Glutamic Acid	120-129	homeostatic iron regulator	Homo sapiens	24-27	
19560233-10	2011	This study demonstrates HFE cellular effects that extend beyond iron regulation, and suggests that H63D HFE may promote glutamate toxicity.	Glutamic Acid	120-129	homeostatic iron regulator	Homo sapiens	104-107	
21346098-7	2011	At the cellular level, the HFE mutant protein resulting from the H63D HFE gene variant is associated with iron dyshomeostasis, increased oxidative stress, glutamate release, tau phosphorylation, and alteration in inflammatory response, each of which is under investigation as a contributing factor to neurodegenerative diseases.	Glutamic Acid	155-164	homeostatic iron regulator	Homo sapiens	70-73	
19590084-4	2009	Although treatment of mitochondria with Glu or guanosine diphosphate had no effect, retinal increased and carboxyatractylate alone or in combination with Glu decreased proton conductance relative to control proton conductance in both HFE and LFE mitochondria.	Glutamic Acid	154-157	homeostatic iron regulator	Homo sapiens	234-237