PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20890990-1 2010 Deletion of the tumor suppressor gene p53 has been shown to improve the outcome in experimental models of focal cerebral ischemia and kainate-induced seizures. Kainic Acid 134-141 transformation related protein 53, pseudogene Mus musculus 38-41 27000207-9 2016 Finally, using a kainic acid-induced seizure model in mice, we show that alterations of Mdm2-p53-Nedd4-2 signaling affect seizure susceptibility. Kainic Acid 17-28 transformation related protein 53, pseudogene Mus musculus 93-96 22612817-0 2012 Acute, but reversible, kainic acid-induced DNA damage in hippocampal CA1 pyramidal cells of p53-deficient mice. Kainic Acid 23-34 transformation related protein 53, pseudogene Mus musculus 92-95 21368852-5 2010 Analysis of electroencephalogram (EEG) recordings during status epilepticus induced by intra-amygdala kainic acid (KA) showed that seizures lasted significantly longer in p53-deficient mice compared with wild-type animals. Kainic Acid 102-113 transformation related protein 53, pseudogene Mus musculus 171-174 19890018-3 2010 In the present study, we report that status epilepticus (SE) triggered by intra-amygdala kainic acid in mice causes rapid p53 accumulation and subsequent hippocampal damage. Kainic Acid 89-100 transformation related protein 53, pseudogene Mus musculus 122-125 16216017-8 2005 Addition of pifithrin-alpha, a p53 inhibitor, or expression of a dominant-negative p53 rescued neurons from kainate-induced excitotoxic cell death in primary cortical cultures derived from wildtype, DNA-PKcs heterozygous, or DNA-PKcs null neonatal mice. Kainic Acid 108-115 transformation related protein 53, pseudogene Mus musculus 83-86 11589996-2 2001 In the present study, we have investigated the implication of three molecules of this cascade, p53, Bax and caspase-3, in neuronal death induced by kainic acid (KA) administration in mouse hippocampus. Kainic Acid 148-159 transformation related protein 53, pseudogene Mus musculus 95-98 8824316-7 1996 Neurons containing at least one copy of p53 were severely damaged by exposure to kainic acid or glutamate. Kainic Acid 81-92 transformation related protein 53, pseudogene Mus musculus 40-43 8778285-4 1996 Subcutaneous injection of kainic acid, a potent excitotoxin, induced comparable seizures in both wild-type mice (+/+) and mice deficient in p53 (-/-). Kainic Acid 26-37 transformation related protein 53, pseudogene Mus musculus 140-143 12098486-3 2002 In this work, we studied if there is a putative implication of the p53 and the caspase-3 proteins in kainic acid (KA) and N-methyl-D-aspartic acid (NMDA)-induced apoptosis in organotypic cultures and if there is any relationship between their respective expressions. Kainic Acid 101-112 transformation related protein 53, pseudogene Mus musculus 67-70 9839726-0 1998 Kainic acid-induced neuronal loss and glial changes in the hippocampal CA3 of p53-deficient mouse. Kainic Acid 0-11 transformation related protein 53, pseudogene Mus musculus 78-81