PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15857425-0	2005	Time-dependent effect of kainate-induced seizures on glutamate receptor GluR5, GluR6, and GluR7 mRNA and Protein Expression in rat hippocampus.	Kainic Acid	25-32	glutamate ionotropic receptor kainate type subunit 1	Rattus norvegicus	72-77	
15821949-2	2005	Compounds have been identified that have preferential activity at AMPA receptors (LY302679), whereas others (LY377770) have affinity for GluR5-kainic acid preferring subunit, which is activated by ATPA and kainic acid.	Kainic Acid	143-154	glutamate ionotropic receptor kainate type subunit 1	Rattus norvegicus	137-142	
15821949-2	2005	Compounds have been identified that have preferential activity at AMPA receptors (LY302679), whereas others (LY377770) have affinity for GluR5-kainic acid preferring subunit, which is activated by ATPA and kainic acid.	Kainic Acid	206-217	glutamate ionotropic receptor kainate type subunit 1	Rattus norvegicus	137-142	
10513575-2	1999	has previously been shown to be a relatively weak AMPA receptor agonist and a very potent agonist at the GluR5 subtype of kainic acid-preferring (S)-glutamic acid ((S)-Glu) receptors.	Kainic Acid	122-133	glutamate ionotropic receptor kainate type subunit 1	Rattus norvegicus	105-110	
10513575-10	1999	Due to desensitization of GluR5 receptors, which could not be fully prevented by treatment with concanavalin A, (S)-ATPA-induced agonist effects were normalized to those of kainic acid.	Kainic Acid	173-184	glutamate ionotropic receptor kainate type subunit 1	Rattus norvegicus	26-31	
10493110-6	1999	LY293558 and the selective GluR5 antagonist, LY382884, had weak antagonist effects on responses evoked by either kainate or (2S,4R)-4-methyl glutamate (IC50 > 300 microM).	Kainic Acid	113-120	glutamate ionotropic receptor kainate type subunit 1	Rattus norvegicus	27-32	
9326306-4	1997	Responses to 30 microM kainate in the presence of LY300168 were virtually abolished by the AMPA and GluR5 kainate receptor competitive antagonist LY293558 (100 microM).	Kainic Acid	23-30	glutamate ionotropic receptor kainate type subunit 1	Rattus norvegicus	100-105	
9099808-1	1997	The mRNAs encoding kainic acid (KA) preferring glutamate receptor subunits (GluR5-7, KA1 and KA2) are differentially expressed in rat brain.	Kainic Acid	19-30	glutamate ionotropic receptor kainate type subunit 1	Rattus norvegicus	76-81	
9203076-5	1997	In the dentate gyrus, resistant to neurodegeneration, pilocarpine and kainate differentially affected the expression of GluR2 and GluR5 mRNAs.	Kainic Acid	70-77	glutamate ionotropic receptor kainate type subunit 1	Rattus norvegicus	130-135	
9203076-9	1997	However, differences in the kainate-and pilocarpine-induced changes in the dentate gyrus at the late time points indicate that alterations in the stoichiometry of GluR2 forms of GluR5 gene expression in this brain region are not a common causal factor responsible for delayed neuronal hyperexcitability.	Kainic Acid	28-35	glutamate ionotropic receptor kainate type subunit 1	Rattus norvegicus	178-183	
23729301-2	2013	We have shown that dapsone (DDS) was able to reduce both neurotoxicity and seizures associated to the administration of kainic acid (KA), an agonist acting on AMPA/KA receptors (GluK1-GluK5).	Kainic Acid	120-131	glutamate ionotropic receptor kainate type subunit 1	Rattus norvegicus	178-183	
20962029-0	2011	The GluK1 (GluR5) Kainate/{alpha}-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonist LY293558 reduces soman-induced seizures and neuropathology.	Kainic Acid	18-25	glutamate ionotropic receptor kainate type subunit 1	Rattus norvegicus	4-9	
20962029-0	2011	The GluK1 (GluR5) Kainate/{alpha}-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonist LY293558 reduces soman-induced seizures and neuropathology.	Kainic Acid	18-25	glutamate ionotropic receptor kainate type subunit 1	Rattus norvegicus	11-16	
17543353-5	2007	The facilitatory and inhibitory effects of kainate were mimicked by the GluR5 subunit selective agonist ATPA.	Kainic Acid	43-50	glutamate ionotropic receptor kainate type subunit 1	Rattus norvegicus	72-77	
17141463-5	2007	As a result, high levels of GluR5 expression associated with strong [(3)H]-kainic acid binding were observed on postnatal days 30 and 60 in the cerebral cortex of rats exposed to glutamate.	Kainic Acid	75-86	glutamate ionotropic receptor kainate type subunit 1	Rattus norvegicus	28-33	
17134593-0	2006	Effect of ketogenic diet on hippocampus mossy fiber sprouting and GluR5 expression in kainic acid induced rat model.	Kainic Acid	86-97	glutamate ionotropic receptor kainate type subunit 1	Rattus norvegicus	66-71	
16624024-0	2006	[Effect of ketogenic diet on hippocampus synaptic reorganization and GluR5 expression in kainic acid induced rat model of epilepsy].	Kainic Acid	89-100	glutamate ionotropic receptor kainate type subunit 1	Rattus norvegicus	69-74