PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19020018-5 2008 These same changes, together with cytoskeletal proteolysis and neuronal cell death, accompany CAST depletion after intrahippocampal kainic acid administration to mice, and are substantially reduced in mice overexpressing human CAST. Kainic Acid 132-143 calpastatin Mus musculus 94-98