PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11368924-5	2001	Specific inhibitors of Ca(2+)-dependent PLA(2) prevented the decrease of a neuronal marker, GluR1, and increase in cPLA(2) and 4-HNE immunoreactivities in slices treated with kainate.	Kainic Acid	175-182	glutamate ionotropic receptor AMPA type subunit 1	Rattus norvegicus	92-97	
9406922-8	1997	In AxCAGluR1-infected cells, the current-voltage (I-V) relationship of response to kainate, a non-desensitizing agonist of AMPA receptors, exhibited a strong inward rectification, indicating the formation of functional GluR1-homomeric channels.	Kainic Acid	83-90	glutamate ionotropic receptor AMPA type subunit 1	Rattus norvegicus	7-12	
9330373-1	1997	The cellular distribution of calpain activation and glutamate receptor 1 (GluR1) subunits of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors and their alterations following kainic acid-induced seizure were evaluated during postnatal development using antibodies specific for spectrin breakdown product and the C-terminus of GluR1 subunits.	Kainic Acid	192-203	glutamate ionotropic receptor AMPA type subunit 1	Rattus norvegicus	52-72	
9330373-1	1997	The cellular distribution of calpain activation and glutamate receptor 1 (GluR1) subunits of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors and their alterations following kainic acid-induced seizure were evaluated during postnatal development using antibodies specific for spectrin breakdown product and the C-terminus of GluR1 subunits.	Kainic Acid	192-203	glutamate ionotropic receptor AMPA type subunit 1	Rattus norvegicus	74-79	
9330373-11	1997	The early increase in GluR1 immunoreactivity in hippocampal pyramidal layer following kainic acid treatment occurred throughout the developmental period, while the later decrease in CA regions, amygdala, and pyriform cortex was observed only in postnatal day 21 animals.	Kainic Acid	86-97	glutamate ionotropic receptor AMPA type subunit 1	Rattus norvegicus	22-27	
11484817-0	2001	Kainate-induced epilepsy alters protein expression of AMPA receptor subunits GluR1, GluR2 and AMPA receptor binding protein in the rat hippocampus.	Kainic Acid	0-7	glutamate ionotropic receptor AMPA type subunit 1	Rattus norvegicus	77-82	
10561704-7	1999	(S)-ATPO also blocked kainic acid agonist effects at GluR1 (K(i) = 2.0 microM), GluR1+2 (K(i) = 3.6 microM), GluR3 (K(i) = 3.6 microM), GluR4 (K(i) = 6.7 microM), and GluR5 (K(i) = 23 microM), but was inactive at GluR6 and GluR6+KA2.	Kainic Acid	22-33	glutamate ionotropic receptor AMPA type subunit 1	Rattus norvegicus	53-58	
10561704-7	1999	(S)-ATPO also blocked kainic acid agonist effects at GluR1 (K(i) = 2.0 microM), GluR1+2 (K(i) = 3.6 microM), GluR3 (K(i) = 3.6 microM), GluR4 (K(i) = 6.7 microM), and GluR5 (K(i) = 23 microM), but was inactive at GluR6 and GluR6+KA2.	Kainic Acid	22-33	glutamate ionotropic receptor AMPA type subunit 1	Rattus norvegicus	80-85	
8738374-5	1996	Intravenous kainate injections resulted in a decrease in GluR1 and GluR2/3 immunoreactivity on the apical dendrites of pyramidal neurons as early as 7 h postinjection.	Kainic Acid	12-19	glutamate ionotropic receptor AMPA type subunit 1	Rattus norvegicus	57-62	
18239782-0	2007	Combined blockade of alpha3beta4 nicotinic acetylcholine receptors and GluR1 AMPA receptors in rats prevents kainate-induced tonic-clonic seizures.	Kainic Acid	109-116	glutamate ionotropic receptor AMPA type subunit 1	Rattus norvegicus	71-76	
18239782-1	2007	Intramuscular injection of IEM-1754, a blocker of cerebral GluR1 AMPA receptors, in doses of 0.5-3.0 mg/kg decreased the incidence of kainate-induced tonic-clonic seizures and mortality rate by 2.7-4 times.	Kainic Acid	134-141	glutamate ionotropic receptor AMPA type subunit 1	Rattus norvegicus	59-64	
7690404-6	1993	PhTX-343 and ArgTX-636 were more or less equally potent (IC50s were 2.8 microM and 3.4 microM, respectively) antagonists of the response of GluR1 to 100 microM kainate.	Kainic Acid	160-167	glutamate ionotropic receptor AMPA type subunit 1	Rattus norvegicus	140-145	
8496162-8	1993	Coexpression of a plasmid for GH and a plasmid for the non-N-methyl-D-aspartate glutamate receptor, GluR1, created chromaffin cells in which Ca(2+)-dependent GH secretion could be stimulated by the glutamatergic agonist kainate.	Kainic Acid	220-227	glutamate ionotropic receptor AMPA type subunit 1	Rattus norvegicus	100-105