PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25657722-0 2014 Overexpression of C-terminal fragment of glutamate receptor 6 prevents neuronal injury in kainate-induced seizure via disassembly of GluR6-PSD-95-MLK3 signaling module. Kainic Acid 90-97 discs large MAGUK scaffold protein 4 Rattus norvegicus 139-145 25657722-5 2014 Our findings revealed that overexpression of GluR6c inhibited the interaction of GluR6 with PSD95 and prevented the kainate-induced activation of JNK, MLK3 and MKK7. Kainic Acid 116-123 discs large MAGUK scaffold protein 4 Rattus norvegicus 92-97 19477222-2 2009 Here, we investigate whether overexpression of the PDZ1 domain of PSD-95 protein could suppress the binding of GluR6 with PSD-95 and the activation of MLK3, MKK7 (mitogen-activated kinase kinase 7) and JNK1/2, and rescused neuronal cell death induced by kainic acid. Kainic Acid 254-265 discs large MAGUK scaffold protein 4 Rattus norvegicus 66-72 19477222-4 2009 Further studies indicated that overexpression of PDZ1 could inhibit the enhancement of binding of GluR6 to PSD-95 and prevent the activation of MLK3, MKK7 and JNK1/2 induced by kainic acid. Kainic Acid 177-188 discs large MAGUK scaffold protein 4 Rattus norvegicus 107-113 19428647-0 2009 Alterations of NR2B and PSD-95 expression in hippocampus of kainic acid-exposed rats with behavioural deficits. Kainic Acid 60-71 discs large MAGUK scaffold protein 4 Rattus norvegicus 24-30 16624817-3 2006 In this study, we show that kainate can enhance the assembly of the GluR6-PSD95-MLK3 module and facilitate the phosphorylation of JNK in rat hippocampal CA1 and CA3/dentate gyrus (DG) subfields. Kainic Acid 28-35 discs large MAGUK scaffold protein 4 Rattus norvegicus 74-79