PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18942155-7 2008 The developed electrophoretically mediated microanalysis method was applied for the kinetics study of FMO3 using clozapine as a substrate probe. Clozapine 113-122 flavin containing dimethylaniline monoxygenase 3 Homo sapiens 102-106 9840430-3 1998 In vitro metabolism of clozapine was investigated using human CYP1A1, CYP1A2, CYP2C8, CYP2E1, CYP2C9-arg144, CYP2C9-cys144, CYP2C19, CYP2D6, CYP3A4, CYP3A5 and FMO3 supplemented with an NADPH generating system. Clozapine 23-32 flavin containing dimethylaniline monoxygenase 3 Homo sapiens 160-164 10546928-0 1999 Flavin monooxygenase 3 (FMO3) polymorphism in a white population: allele frequencies, mutation linkage, and functional effects on clozapine and caffeine metabolism. Clozapine 130-139 flavin containing dimethylaniline monoxygenase 3 Homo sapiens 24-28 10546928-3 1999 We therefore wanted to analyze population frequencies and allelic linkage of FMO3 mutations and their functional effect on the metabolism of clozapine and caffeine. Clozapine 141-150 flavin containing dimethylaniline monoxygenase 3 Homo sapiens 77-81 28084789-3 2017 RESULTS: The apparent Km with clozapine as substrate and inhibition of hFMO3 by methimazole were explored for immobilized hFMO3 and were found to be comparable to literature values. Clozapine 30-39 flavin containing dimethylaniline monoxygenase 3 Homo sapiens 122-127