PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33273059-7 2021 We demonstrate that AZD0364 in combination with the MEK1/2 inhibitor selumetinib (AZD6244, ARRY142886) enhances efficacy in KRAS mutant preclinical models that are moderately sensitive or resistant to MEK1/2 inhibition. N-(3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl)-2-methyl-2-((5-(trifluoromethyl)pyridin-2-yl)oxy)propanamide 20-27 mitogen-activated protein kinase kinase 1 Homo sapiens 201-207