PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17872379-1	2008	A number of amino acids essential for Gs coupling, i.e. hot spots, were identified after in vitro Ala-scanning mutagenesis of the cytosolic extensions of helices 3, 5, and 6 and of intracellular loops 2 and 3 (IL2 and IL3) of the human LH receptor (LHR).	Alanine	98-101	interleukin 3	Homo sapiens	218-221	
7957082-7	1994	In contrast, alanine substitutions of these residues only marginally reduced the conversion of IL-3 binding to high affinity by beta c.	Alanine	13-20	interleukin 3	Homo sapiens	95-99	
15279907-5	2004	Alanine substitution of the three basic residues present in the IL3-BXXBB (IL3-AXXAA mutant) yielded a < or =60 kDa possibly under-glycosylated form of the FSHR, whereas the same substitutions in the Ctail resulted in the immature >62 kDa form of the receptor; both AXXAA hFSHR mutants completely failed to bind agonist and activate effector.	Alanine	0-7	interleukin 3	Homo sapiens	64-67	
15279907-5	2004	Alanine substitution of the three basic residues present in the IL3-BXXBB (IL3-AXXAA mutant) yielded a < or =60 kDa possibly under-glycosylated form of the FSHR, whereas the same substitutions in the Ctail resulted in the immature >62 kDa form of the receptor; both AXXAA hFSHR mutants completely failed to bind agonist and activate effector.	Alanine	0-7	interleukin 3	Homo sapiens	75-78	
14967141-6	2004	IL-3 induces BAD phosphorylation at threonine 201, and replacement of threonine 201 by alanine generates a BAD mutant, which promotes IL-3 withdrawal-induced apoptosis.	Alanine	87-94	interleukin 3	Homo sapiens	134-138	
11590166-7	2001	Substitution of either residue with alanine results into a dominant negative mutant that overrides the survival effect of IL-3.	Alanine	36-43	interleukin 3	Homo sapiens	122-126	
8824238-5	1996	Substitution of this whole predicted loop region with alanines completely abrogated high affinity binding of GM-CSF, IL-3, and IL-5.	Alanine	54-62	interleukin 3	Homo sapiens	117-121