PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15196988-5 2004 In CYP2A6, the amino acid residues at position 117 and 372 are valine (Val) and arginine (Arg), respectively; whereas in CYP2A13, they are alanine (Ala) and histidine (His). Alanine 139-146 cytochrome P450 family 2 subfamily A member 6 Homo sapiens 3-9 15196988-5 2004 In CYP2A6, the amino acid residues at position 117 and 372 are valine (Val) and arginine (Arg), respectively; whereas in CYP2A13, they are alanine (Ala) and histidine (His). Alanine 148-151 cytochrome P450 family 2 subfamily A member 6 Homo sapiens 3-9 15196988-6 2004 Kinetic analysis revealed that the catalytic efficiency (Vmax/Km) of the CYP2A6 Val(117)--> Ala and Arg(372)--> His mutants was drastically reduced (0.41 and 0.64 versus 3.23 for the wild-type CYP2A6 protein). Alanine 95-98 cytochrome P450 family 2 subfamily A member 6 Homo sapiens 73-79 15196988-6 2004 Kinetic analysis revealed that the catalytic efficiency (Vmax/Km) of the CYP2A6 Val(117)--> Ala and Arg(372)--> His mutants was drastically reduced (0.41 and 0.64 versus 3.23 for the wild-type CYP2A6 protein). Alanine 95-98 cytochrome P450 family 2 subfamily A member 6 Homo sapiens 199-205