PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19766653-4 2009 To this end, we utilize a recombinant variant of human alpha-lactalbumin in which all eight cysteine residues are substituted for alanines (rHLA(all-Ala)), rendering the protein nonnative and biologically inactive under all conditions. Alanine 130-138 lactalbumin alpha Homo sapiens 55-72 19766653-4 2009 To this end, we utilize a recombinant variant of human alpha-lactalbumin in which all eight cysteine residues are substituted for alanines (rHLA(all-Ala)), rendering the protein nonnative and biologically inactive under all conditions. Alanine 149-152 lactalbumin alpha Homo sapiens 55-72 9653039-4 1998 In order to understand the mechanism for formation of the native-like tertiary topology, we substituted alanine for each of the 23 buried residues in the alpha-helical domain of alpha-LA and determined the effect of these substitutions on the Ceff for formation of the 28-111 disulfide bond. Alanine 104-111 lactalbumin alpha Homo sapiens 178-186 19618277-2 2009 In the alpha-LA variant, the eight cysteine residues in the protein have been replaced by alanines (all-Ala alpha-LA). Alanine 90-98 lactalbumin alpha Homo sapiens 7-15 19618277-2 2009 In the alpha-LA variant, the eight cysteine residues in the protein have been replaced by alanines (all-Ala alpha-LA). Alanine 90-98 lactalbumin alpha Homo sapiens 108-116 10504730-4 1999 A variant of alpha-LA, in which all eight cysteines have been mutated to alanine (all-Ala alpha-LA), has been studied using NMR spectroscopy. Alanine 73-80 lactalbumin alpha Homo sapiens 13-21 10504730-4 1999 A variant of alpha-LA, in which all eight cysteines have been mutated to alanine (all-Ala alpha-LA), has been studied using NMR spectroscopy. Alanine 73-80 lactalbumin alpha Homo sapiens 90-98 32885978-2 2020 Here, we demonstrate that alpha-lactalbumin/polyethylene oxide (ALA/PEO) electrospun nanofibers constitute an efficient oromucosal delivery system for fast-onset nicotine delivery of high relevance for acute dosing NRT applications. Alanine 64-67 lactalbumin alpha Homo sapiens 26-43