PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
2736674-1	1989	The effects of the anti-wetting agent perfluoro-n-decanoic acid (PFDA) on various glutathione S-transferase (GST) enzyme activities were studied in vitro and in vivo.	perfluorodecanoic acid	38-63	glutathione S-transferase kappa 1	Homo sapiens	82-107	
2736674-1	1989	The effects of the anti-wetting agent perfluoro-n-decanoic acid (PFDA) on various glutathione S-transferase (GST) enzyme activities were studied in vitro and in vivo.	perfluorodecanoic acid	38-63	glutathione S-transferase kappa 1	Homo sapiens	109-112	
2736674-1	1989	The effects of the anti-wetting agent perfluoro-n-decanoic acid (PFDA) on various glutathione S-transferase (GST) enzyme activities were studied in vitro and in vivo.	perfluorodecanoic acid	65-69	glutathione S-transferase kappa 1	Homo sapiens	82-107	
2736674-1	1989	The effects of the anti-wetting agent perfluoro-n-decanoic acid (PFDA) on various glutathione S-transferase (GST) enzyme activities were studied in vitro and in vivo.	perfluorodecanoic acid	65-69	glutathione S-transferase kappa 1	Homo sapiens	109-112	
2736674-2	1989	In addition the effects of PFDA treatment on the amount of some glutathione S-transferase subunits and their corresponding translatable mRNA were studied in vivo.	perfluorodecanoic acid	27-31	glutathione S-transferase kappa 1	Homo sapiens	64-89	
2736674-3	1989	PFDA like some other peroxisome proliferators was a non-competitive inhibitor of several GST enzyme activities in vitro.	perfluorodecanoic acid	0-4	glutathione S-transferase kappa 1	Homo sapiens	89-92	
2736674-4	1989	In vivo PFDA reduced the enzyme activity towards substrates which are indicative for the Ya, Yb1 and Yb2 subunits of GSTs to a larger extent than the enzyme activity towards the substrate indicative for the Yc subunit.	perfluorodecanoic acid	8-12	glutathione S-transferase kappa 1	Homo sapiens	117-121	
2736674-5	1989	Whereas the reduction of GST enzyme activities by other peroxisome proliferators was shown to be caused by an inhibition of the relevant enzymes in vivo, PFDA was found to decrease the GST enzyme activities at least in part by lowering the amount of the various GST subunits in vivo due to a lowered concentration of translatable mRNA coding for these enzymes.	perfluorodecanoic acid	154-158	glutathione S-transferase kappa 1	Homo sapiens	185-188	
2736674-5	1989	Whereas the reduction of GST enzyme activities by other peroxisome proliferators was shown to be caused by an inhibition of the relevant enzymes in vivo, PFDA was found to decrease the GST enzyme activities at least in part by lowering the amount of the various GST subunits in vivo due to a lowered concentration of translatable mRNA coding for these enzymes.	perfluorodecanoic acid	154-158	glutathione S-transferase kappa 1	Homo sapiens	185-188	
2736674-6	1989	In addition PFDA abolished the inducibility of GST mRNAs by phenobarbital.	perfluorodecanoic acid	12-16	glutathione S-transferase kappa 1	Homo sapiens	47-50	
2736674-7	1989	Thus PFDA might be an interesting tool for mechanistic studies of the control of GST expression in the liver.	perfluorodecanoic acid	5-9	glutathione S-transferase kappa 1	Homo sapiens	81-84