PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10965884-0 2000 The peroxisome proliferator perfluorodecanoic acid inhibits the peripheral-type benzodiazepine receptor (PBR) expression and hormone-stimulated mitochondrial cholesterol transport and steroid formation in Leydig cells. perfluorodecanoic acid 28-50 translocator protein Mus musculus 64-103 10965884-0 2000 The peroxisome proliferator perfluorodecanoic acid inhibits the peripheral-type benzodiazepine receptor (PBR) expression and hormone-stimulated mitochondrial cholesterol transport and steroid formation in Leydig cells. perfluorodecanoic acid 28-50 translocator protein Mus musculus 105-108 10965884-11 2000 Further studies indicated that PFDA did not affect PBR transcription, but it rather accelerated PBR mRNA decay. perfluorodecanoic acid 31-35 translocator protein Mus musculus 96-99 10965884-12 2000 Taken together, these data suggest that PFDA inhibits the Leydig cell steroidogenesis by affecting PBR mRNA stability, thus inhibiting PBR expression, cholesterol transport into the mitochondria, and the subsequent steroid formation. perfluorodecanoic acid 40-44 translocator protein Mus musculus 99-102 10965884-12 2000 Taken together, these data suggest that PFDA inhibits the Leydig cell steroidogenesis by affecting PBR mRNA stability, thus inhibiting PBR expression, cholesterol transport into the mitochondria, and the subsequent steroid formation. perfluorodecanoic acid 40-44 translocator protein Mus musculus 135-138 10965884-13 2000 Moreover, this action of PFDA on PBR mRNA stability indicates a new mechanism of action of peroxisome proliferators distinct from the classic transcription-mediated regulation of target genes. perfluorodecanoic acid 25-29 translocator protein Mus musculus 33-36