PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23053988-8 2012 This suggests that the IGF-I promoting effect of ALA may be mediated by the PPARalpha pathway. alpha-Linolenic Acid 49-52 peroxisome proliferator activated receptor alpha Homo sapiens 76-85 24396573-4 2013 Alpha Linolenic Acid (LA), and Eicosapentaenoic Acid (EPA) on the PPARalpha and ACAT1 mRNA expression by Real time PCR and cholesterol homeostasis in THP-1 macrophages derived foam cells. alpha-Linolenic Acid 0-20 peroxisome proliferator activated receptor alpha Homo sapiens 66-75 19725980-5 2009 METHODS: This study examined effects of c9, t11-conjugated linoleic acid(c9, t11-CLA), alpha linolenic acid (LA), eicosapentaenoic acid (EPA) on the PPARalpha and ACAT1 genes expression by using Real time PCR and cholesterol homeostasis in THP-1 macrophages derived foam cells. alpha-Linolenic Acid 87-107 peroxisome proliferator activated receptor alpha Homo sapiens 149-158 12906165-6 2002 Treatment of HUVECs with PPARalpha and PPAR gamma activators--linolenic acid, linoleic acid, oleic acid and prostaglandin J2 respectively, but not with stearic acid could augment PAI-1 mRNA expression and protein secretion in a concentration-dependent manner. alpha-Linolenic Acid 62-76 peroxisome proliferator activated receptor alpha Homo sapiens 25-34 19228394-7 2009 CONCLUSION: Formation of EPA and DHA was highest at an administered LA/ALA ratio of 1:1, although gene expression of PPARalpha, SREBP-1c and D5D involved in ALA elongation were higher in the presence of ALA solely. alpha-Linolenic Acid 157-160 peroxisome proliferator activated receptor alpha Homo sapiens 117-126 19228394-7 2009 CONCLUSION: Formation of EPA and DHA was highest at an administered LA/ALA ratio of 1:1, although gene expression of PPARalpha, SREBP-1c and D5D involved in ALA elongation were higher in the presence of ALA solely. alpha-Linolenic Acid 157-160 peroxisome proliferator activated receptor alpha Homo sapiens 117-126 12667383-7 2003 Treatment of HUVECs with PPARalpha and PPARgamma activators-linolenic acid, linoleic acid, oleic acid and prostaglandin J(2), but not with stearic acid could augment PAI-I mRNA expression and protein secretion in a concentration-dependent manner. alpha-Linolenic Acid 60-74 peroxisome proliferator activated receptor alpha Homo sapiens 25-34 19667161-13 2009 The simultaneous treatment with 1,25(OH)2D3 partially antagonised the DHA- and alpha-linolenicacid (ALA)-induced up-regulation of PPAR expression. alpha-Linolenic Acid 79-98 peroxisome proliferator activated receptor alpha Homo sapiens 130-134 19667161-13 2009 The simultaneous treatment with 1,25(OH)2D3 partially antagonised the DHA- and alpha-linolenicacid (ALA)-induced up-regulation of PPAR expression. alpha-Linolenic Acid 100-103 peroxisome proliferator activated receptor alpha Homo sapiens 130-134 19667161-15 2009 Simultaneous treatment with the PPAR ligands bezafibrate or ALA resulted in an up to 6-fold reduction of the 1,25(OH)2D3-induced elevation of the 1alpha,25-dihydroxyvitamin D3-24-hydroxylase (CYP24A1) expression. alpha-Linolenic Acid 60-63 peroxisome proliferator activated receptor alpha Homo sapiens 32-36 35138848-3 2022 Correspondingly, in the fish fed diet with high ALA levels, the mRNA levels of genes related to LC-PUFA biosynthesis including fads2, elovl5, and pparalpha in the intestine and elovl5 in the liver were increased, and the muscular n-3 LC-PUFA levels and textures were improved. alpha-Linolenic Acid 48-51 peroxisome proliferator activated receptor alpha Homo sapiens 146-155