PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23946803-7 2013 COX-2 activity and gene expression levels were significantly decreased by ALA from 20 muM. alpha-Linolenic Acid 74-77 prostaglandin-endoperoxide synthase 2 Homo sapiens 0-5 23946803-13 2013 PPAR-gamma activation and COX-2 inhibition serve as two signaling pathways for the inhibitory effects of ALA on RCC cell proliferation. alpha-Linolenic Acid 105-108 prostaglandin-endoperoxide synthase 2 Homo sapiens 26-31 23946803-0 2013 alpha-linolenic acid inhibits human renal cell carcinoma cell proliferation through PPAR-gamma activation and COX-2 inhibition. alpha-Linolenic Acid 0-20 prostaglandin-endoperoxide synthase 2 Homo sapiens 110-115 15741054-1 2005 The bioactivity of stearidonic acid (SDA, 18:4n-3) and alpha-linolenic acid (LNA, 18:3n-3) on cyclooxygenase-2 (COX-2) enzyme expression and prostaglandin E2 (PGE2) production has not been evaluated. alpha-Linolenic Acid 55-75 prostaglandin-endoperoxide synthase 2 Homo sapiens 94-110 15741054-1 2005 The bioactivity of stearidonic acid (SDA, 18:4n-3) and alpha-linolenic acid (LNA, 18:3n-3) on cyclooxygenase-2 (COX-2) enzyme expression and prostaglandin E2 (PGE2) production has not been evaluated. alpha-Linolenic Acid 55-75 prostaglandin-endoperoxide synthase 2 Homo sapiens 112-117 7642610-4 1995 Comparisons of kcat/Km values indicate that the order of efficiency of oxygenation is arachidonate > dihomo-gamma-linolenate > linoleate > alpha-linolenate for both isozymes; while the order of efficiency was the same for hPGHS-1 and hPGHS-2, alpha-linolenate was a particularly poor substrate for hPGHS-1. alpha-Linolenic Acid 148-164 prostaglandin-endoperoxide synthase 2 Homo sapiens 243-250 7642610-4 1995 Comparisons of kcat/Km values indicate that the order of efficiency of oxygenation is arachidonate > dihomo-gamma-linolenate > linoleate > alpha-linolenate for both isozymes; while the order of efficiency was the same for hPGHS-1 and hPGHS-2, alpha-linolenate was a particularly poor substrate for hPGHS-1. alpha-Linolenic Acid 252-268 prostaglandin-endoperoxide synthase 2 Homo sapiens 243-250 29668263-6 2018 Inhibitory effect of ALA on generation of NO and cytokines was mediated by down-regulation of inducible nitric oxide synthase and cyclooxygenase-2 protein and mRNA expressions. alpha-Linolenic Acid 21-24 prostaglandin-endoperoxide synthase 2 Homo sapiens 130-146