PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32951572-3 2020 In 2003, the first anti-tumor gene therapy drug rAd-p53 (recombinant human p53 adenovirus), trade name Gendicine , was approved by the China Food and Drug Administration (CFDA) for treatment of head and neck squamous cell carcinoma (HNSCC) in combination with radiotherapy. gendicine 103-112 tumor protein p53 Homo sapiens 52-55 32951572-3 2020 In 2003, the first anti-tumor gene therapy drug rAd-p53 (recombinant human p53 adenovirus), trade name Gendicine , was approved by the China Food and Drug Administration (CFDA) for treatment of head and neck squamous cell carcinoma (HNSCC) in combination with radiotherapy. gendicine 103-112 tumor protein p53 Homo sapiens 75-78 29338444-1 2018 Gendicine (recombinant human p53 adenovirus), developed by Shenzhen SiBiono GeneTech Co. Ltd., was approved in 2003 by the China Food and Drug Administration (CFDA) as a first-in-class gene therapy product to treat head and neck cancer, and entered the commercial market in 2004. gendicine 0-9 tumor protein p53 Homo sapiens 29-32 27843742-1 2016 To compare clinical curative effects and toxicity of recombinant human adenovirus-p53 injection (rAd-p53, Gendicine) combining chemoradiotherapy (CRT)/radiotherapy (RT) with those obtained with CRT/RT alone in nasopharyngeal carcinoma (NPC). gendicine 106-115 tumor protein p53 Homo sapiens 82-85 20679889-1 2010 The objective of this study is to explore the safety, efficacy, and administration method of the recombinant adenovirus p53 gene (rAd-p53, or gendicine) in the treatment of pulmonary metastasis tumor from advanced hepatocellular carcinoma (HCC). gendicine 142-151 tumor protein p53 Homo sapiens 120-123 16188130-1 2005 OBJECTIVE: To evaluate the efficacy and safety of recombinant adenovirus-p53 gene (Gendicine) therapy combined with radiotherapy for head and neck squamous-cell carcinoma (HNSCC). gendicine 83-92 tumor protein p53 Homo sapiens 73-76 16188130-10 2005 The apparent improved results of combined therapy with Gendicine and radiation suggest that p53 gene therapy has promising therapeutic potential in cancer treatment. gendicine 55-64 tumor protein p53 Homo sapiens 92-95 24457472-4 2014 The patients in the treatment group were given arterial infusion of p53 gene (Gendicine, Shenzhen Sibiono GeneTech Co, Ltd) with Gendicine (10vp) combined with hydroxycamptothecin (20 mg), once a week, for a course continuously for 3 weeks. gendicine 78-87 tumor protein p53 Homo sapiens 68-71 24457472-4 2014 The patients in the treatment group were given arterial infusion of p53 gene (Gendicine, Shenzhen Sibiono GeneTech Co, Ltd) with Gendicine (10vp) combined with hydroxycamptothecin (20 mg), once a week, for a course continuously for 3 weeks. gendicine 129-138 tumor protein p53 Homo sapiens 68-71 19882171-1 2010 OBJECTIVE: The purpose of our study was to evaluate the feasibility and treatment outcomes of recombinant adenovirus-p53 (rAd-p53, trademarked as Gendicine) combined with fractionated stereotactic radiotherapy (fSRT) in treatment of primary hepatocellular carcinoma (HCC). gendicine 146-155 tumor protein p53 Homo sapiens 117-120 19318914-4 2009 The patient was first treated with adenovirus-mediated wild-type p53 gene (Ad-p53, gendicine) combined with oxaliplatin (200 mg) and transcatheter arterial chemoembolization or transcatheter arterial chemotherapy for two cycles. gendicine 83-92 tumor protein p53 Homo sapiens 65-68