PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26313261-0 2015 8-Chloroadenosine Sensitivity in Renal Cell Carcinoma Is Associated with AMPK Activation and mTOR Pathway Inhibition. 8-chloroadenosine 0-17 protein kinase AMP-activated catalytic subunit alpha 1 Homo sapiens 73-77 26313261-11 2015 We thus infer that 8-chloroadenosine may be effective in RCC by activating AMPK and inhibiting the mTOR pathway. 8-chloroadenosine 19-36 protein kinase AMP-activated catalytic subunit alpha 1 Homo sapiens 75-79 26313261-5 2015 In time-course experiments, 8-chloroadenosine treatment rapidly activated AMPK, measured by AMPK and ACC phosphorylation, and subsequently caused dephosphorylation of p70S6K and ribosomal protein RPS6 in the sensitive cell lines. 8-chloroadenosine 28-45 protein kinase AMP-activated catalytic subunit alpha 1 Homo sapiens 74-78 26313261-5 2015 In time-course experiments, 8-chloroadenosine treatment rapidly activated AMPK, measured by AMPK and ACC phosphorylation, and subsequently caused dephosphorylation of p70S6K and ribosomal protein RPS6 in the sensitive cell lines. 8-chloroadenosine 28-45 protein kinase AMP-activated catalytic subunit alpha 1 Homo sapiens 92-96