PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16722661-0 2006 Identification of a new class of low molecular weight antagonists against the chemokine receptor CXCR4 having the dipicolylamine-zinc(II) complex structure. 2,2'-dipicolylamine 114-128 C-X-C motif chemokine receptor 4 Homo sapiens 97-102 30772128-4 2019 Furthermore, selected compounds 3, 8, 9, 19 and 21 with spatial distances between the next carbon to Dpa and the next carbon to cyclam within the range of 6.5-7.5 A showed potent binding affinity selective for CXCR4 with IC50 values of 1.6, 7.9, 5.7, 3.5 and 4.5 nM, respectively, with corresponding high anti-HIV activity with EC50s of 28, 13, 21, 28 and 61 nM, respectively, in the presence of zinc (II) ion. 2,2'-dipicolylamine 101-104 C-X-C motif chemokine receptor 4 Homo sapiens 210-215 23086703-1 2013 Low-molecular-weight CXCR4 ligands based on known lead compounds including the 14-mer peptide T140, the cyclic pentapeptide FC131, peptide mimetics, and dipicolylamine-containing compounds were designed and synthesized. 2,2'-dipicolylamine 153-167 C-X-C motif chemokine receptor 4 Homo sapiens 21-26