PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19557111-2	2009	PDEs play an important role in signal transduction by regulating the intracellular concentration of cyclic nucleotides.	Nucleotides, Cyclic	100-118	phosphodiesterase 11A	Homo sapiens	0-4	
27625633-2	2016	Phosphodiesterases (PDEs) are enzymes that regulate cyclic nucleotide levels, including cyclic adenosine monophosphate (cAMP).	Nucleotides, Cyclic	52-69	phosphodiesterase 11A	Homo sapiens	0-18	
27625633-2	2016	Phosphodiesterases (PDEs) are enzymes that regulate cyclic nucleotide levels, including cyclic adenosine monophosphate (cAMP).	Nucleotides, Cyclic	52-69	phosphodiesterase 11A	Homo sapiens	20-24	
25056711-5	2015	At specific intracellular locations, individual PDEs, together with pathway-specific signaling molecules, regulators, and effectors, are incorporated into specific signalosomes, where they facilitate and regulate compartmentalization of cyclic nucleotide signaling pathways and specific cellular functions.	Nucleotides, Cyclic	237-254	phosphodiesterase 11A	Homo sapiens	48-52	
19689430-6	2009	We have developed a scintillation proximity-based assay to directly measure cyclic nucleotide binding to the PDE2A, PDE10A and PDE11A GAF domains, and in the present study we demonstrate binding of cyclic nucleotides to the PDE10A and PDE11A GAF domains.	Nucleotides, Cyclic	76-93	phosphodiesterase 11A	Homo sapiens	127-133	
19689430-6	2009	We have developed a scintillation proximity-based assay to directly measure cyclic nucleotide binding to the PDE2A, PDE10A and PDE11A GAF domains, and in the present study we demonstrate binding of cyclic nucleotides to the PDE10A and PDE11A GAF domains.	Nucleotides, Cyclic	76-93	phosphodiesterase 11A	Homo sapiens	235-241	
19689430-6	2009	We have developed a scintillation proximity-based assay to directly measure cyclic nucleotide binding to the PDE2A, PDE10A and PDE11A GAF domains, and in the present study we demonstrate binding of cyclic nucleotides to the PDE10A and PDE11A GAF domains.	Nucleotides, Cyclic	198-216	phosphodiesterase 11A	Homo sapiens	127-133	
19689430-6	2009	We have developed a scintillation proximity-based assay to directly measure cyclic nucleotide binding to the PDE2A, PDE10A and PDE11A GAF domains, and in the present study we demonstrate binding of cyclic nucleotides to the PDE10A and PDE11A GAF domains.	Nucleotides, Cyclic	198-216	phosphodiesterase 11A	Homo sapiens	235-241	
16767104-1	2006	Phosphodiesterases (PDEs) regulate cyclic nucleotide levels.	Nucleotides, Cyclic	35-52	phosphodiesterase 11A	Homo sapiens	0-18	
16767104-1	2006	Phosphodiesterases (PDEs) regulate cyclic nucleotide levels.	Nucleotides, Cyclic	35-52	phosphodiesterase 11A	Homo sapiens	20-24	
33127481-1	2021	Phosphodiesterases catalyze the hydrolysis of cyclic nucleotides and maintain physiologic levels of intracellular concentrations of cyclic adenosine and guanosine mono-phosphate (cAMP and cGMP, respectively).	Nucleotides, Cyclic	46-64	phosphodiesterase 11A	Homo sapiens	0-18