PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34890760-8	2022	NaB treatment upregulated the expression of the growth factor-related factors PPARgamma, CREB, and BDNF in the brain tissues of HFD-fed mice.	nab	0-3	cAMP responsive element binding protein 1	Mus musculus	89-93	
27342118-3	2016	NaB induced the activation of CREB in hippocampal neurons via protein kinase A (PKA), which was responsible for the upregulation of plasticity-related molecules.	nab	0-3	cAMP responsive element binding protein 1	Mus musculus	30-34	
27342118-5	2016	However, oral treatment of cinnamon and NaB increased spatial memory consolidation-induced activation of CREB and expression of plasticity-related molecules in the hippocampus of poor-learning mice and converted poor learners into good learners.	nab	40-43	cAMP responsive element binding protein 1	Mus musculus	105-109	
23475543-6	2013	Furthermore, activation of cAMP response element binding (CREB) protein, but not NF-kappaB, by NaB, abrogation of NaB-induced expression of neurotrophic factors by siRNA knockdown of CREB and the recruitment of CREB and CREB-binding protein to the BDNF promoter by NaB suggest that NaB exerts its neurotrophic effect through the activation of CREB.	nab	95-98	cAMP responsive element binding protein 1	Mus musculus	58-62	
23475543-6	2013	Furthermore, activation of cAMP response element binding (CREB) protein, but not NF-kappaB, by NaB, abrogation of NaB-induced expression of neurotrophic factors by siRNA knockdown of CREB and the recruitment of CREB and CREB-binding protein to the BDNF promoter by NaB suggest that NaB exerts its neurotrophic effect through the activation of CREB.	nab	114-117	cAMP responsive element binding protein 1	Mus musculus	58-62	
23475543-6	2013	Furthermore, activation of cAMP response element binding (CREB) protein, but not NF-kappaB, by NaB, abrogation of NaB-induced expression of neurotrophic factors by siRNA knockdown of CREB and the recruitment of CREB and CREB-binding protein to the BDNF promoter by NaB suggest that NaB exerts its neurotrophic effect through the activation of CREB.	nab	114-117	cAMP responsive element binding protein 1	Mus musculus	183-187	
23475543-6	2013	Furthermore, activation of cAMP response element binding (CREB) protein, but not NF-kappaB, by NaB, abrogation of NaB-induced expression of neurotrophic factors by siRNA knockdown of CREB and the recruitment of CREB and CREB-binding protein to the BDNF promoter by NaB suggest that NaB exerts its neurotrophic effect through the activation of CREB.	nab	114-117	cAMP responsive element binding protein 1	Mus musculus	183-187	
23475543-8	2013	These results highlight a novel neutrophic property of cinnamon and its metabolite NaB via PKA - CREB pathway, which may be of benefit for various neurodegenerative disorders.	nab	83-86	cAMP responsive element binding protein 1	Mus musculus	97-101