PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15048829-4	2004	In addition to improving the energy balance between folded and unfolded conformers, the algorithm (available in the AMBER-7 and NAB molecular modeling packages) is shown to perform well in more than 50 ns of native-state molecular dynamics (MD) simulations of thioredoxin, protein-A, and ubiquitin, as well as in a simulation of Barnase/Barstar complex formation.	nab	128-131	thioredoxin	Homo sapiens	260-271	
32547098-2	2020	However, the role of thioredoxin-1 (Trx-1) in NaB-induced anti-tumor effect has not been completely clarified.	nab	46-49	thioredoxin	Homo sapiens	21-34	
32547098-2	2020	However, the role of thioredoxin-1 (Trx-1) in NaB-induced anti-tumor effect has not been completely clarified.	nab	46-49	thioredoxin	Homo sapiens	36-41	
32547098-9	2020	Results: NaB treatment significantly inhibited cell growth and decreased Trx-1 protein expression in CRC cells but not in normal colon epithelial cells.	nab	9-12	thioredoxin	Homo sapiens	73-78	
32547098-12	2020	Moreover, downregulation of Trx-1 significantly enhanced NaB-induced inhibitory effects on cell growth and migration, whereas overexpression of Trx-1 attenuated NaB-induced inhibitory effects on growth and migration in CRC cells.	nab	57-60	thioredoxin	Homo sapiens	28-33	
32547098-12	2020	Moreover, downregulation of Trx-1 significantly enhanced NaB-induced inhibitory effects on cell growth and migration, whereas overexpression of Trx-1 attenuated NaB-induced inhibitory effects on growth and migration in CRC cells.	nab	161-164	thioredoxin	Homo sapiens	144-149	
32547098-13	2020	Conclusion: These findings indicate that the NaB-mediated anti-tumor effects on CRC cells are related to downregulation of Trx-1.	nab	45-48	thioredoxin	Homo sapiens	123-128