PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29501442-10 2018 Identified XIAP variants S123N, R233Q, and P257A were associated with an impaired activation of NOD2 signaling after muramyl dipeptide stimulation. Dipeptides 125-134 X-linked inhibitor of apoptosis Homo sapiens 11-15 26953272-11 2017 Muramyl dipeptide-driven cytokine responses and antibacterial autophagy induction are parallel and independent signalling cascades downstream of the NOD2-RIPK2-XIAP complex. Dipeptides 8-17 X-linked inhibitor of apoptosis Homo sapiens 160-164 24611904-3 2014 Based on recent evidence that XIAP is essential for nucleotide-binding and oligomerization domains (NOD)1/2 signalling, we evaluated the use of a simple flow cytometric assay assessing tumour necrosis factor (TNF) production of monocytes in response to NOD2 stimulation by muramyl dipeptides (L18-MDP) for the functional diagnosis of XIAP deficiency. Dipeptides 281-291 X-linked inhibitor of apoptosis Homo sapiens 30-34