PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27099787-1 2016 This study was performed in order to reveal the effect of Noopept (ethyl ester of N-phenylacetyl-Lprolylglycine, GVS-111) on the DNA-binding activity of transcriptional factors (TF) in HEK293 cells transiently transfected with luciferase reporter constructs containing sequences for CREB, NFAT, NF-kappaB, p53, STAT1, GAS, VDR, HSF1, and HIF-1. ethyl ester 67-78 tumor protein p53 Homo sapiens 306-309 24405416-4 2014 Herein we report the design, synthesis and optimization of YH239-EE (ethyl ester of the free carboxylic acid compound YH239), a potent p53-MDM2 antagonizing and apoptosis-inducing agent characterized by a number of leukemia cell lines as well as patient-derived AML blast samples. ethyl ester 69-80 tumor protein p53 Homo sapiens 135-138