PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28338133-3 2017 In particular, many experimental and theoretical studies confirmed that stereoisomers of an important beta2-AR agonist, fenoterol, are associated with diverse mechanisms of binding and activation of beta2-AR. Fenoterol 120-129 adrenoceptor beta 2 Homo sapiens 102-110 28603032-5 2017 Epinephrine effects towards transporter mRNA expression in human hepatocytes were next shown to be correlated to those of the selective beta2-adrenoreceptor (ADR) agonist fenoterol, of the adenylate cyclase activator forskolin and of the cAMP analogue 8-bromo-cAMP. Fenoterol 171-180 adrenoceptor beta 2 Homo sapiens 136-156 28338133-3 2017 In particular, many experimental and theoretical studies confirmed that stereoisomers of an important beta2-AR agonist, fenoterol, are associated with diverse mechanisms of binding and activation of beta2-AR. Fenoterol 120-129 adrenoceptor beta 2 Homo sapiens 199-207 28338133-4 2017 The objective of the present study was to explore the stereoselective binding of fenoterol to beta2-AR through the application of an advanced computational methodology based on enhanced-sampling molecular dynamics simulations and potentials of interactions tailored to investigate the stereorecognition effects. Fenoterol 81-90 adrenoceptor beta 2 Homo sapiens 94-102 25360795-10 2014 CONCLUSIONS: Collectively, our pharmacological investigations indicate that fenoterol-sensitization is modulated by the inhibition/blockage of canonical Wnt/beta-catenin pathway, suggesting a phenomenon of biased agonism in connection with the beta2-adrenoceptor stimulation. Fenoterol 76-85 adrenoceptor beta 2 Homo sapiens 244-262 25930996-2 2015 We reported that fenoterol, a beta2-adrenergic receptor (beta2-AR) agonist, had anti-inflammatory effects in THP-1 cells, a monocytic cell line. Fenoterol 17-26 adrenoceptor beta 2 Homo sapiens 57-65 25930996-4 2015 In this study, we explored the mechanism of beta2-AR stimulation with fenoterol in a lipopolysaccharide (LPS)-induced inflammatory cytokine secretion in THP-1 cells. Fenoterol 70-79 adrenoceptor beta 2 Homo sapiens 44-52 25930996-9 2015 These results suggested the beta2-AR agonist fenoterol inhibited LPS-induced AMPK activation and IL-1beta release via beta-arrestin-2 in THP-1 cells. Fenoterol 45-54 adrenoceptor beta 2 Homo sapiens 28-36 24182991-3 2014 We aimed to assess the association of the effect of fenoterol (beta2-AR agonist) on IL-4-driven and budesonide-induced IgE synthesis with genetic variants of beta2-AR. Fenoterol 52-61 adrenoceptor beta 2 Homo sapiens 63-71 24182991-3 2014 We aimed to assess the association of the effect of fenoterol (beta2-AR agonist) on IL-4-driven and budesonide-induced IgE synthesis with genetic variants of beta2-AR. Fenoterol 52-61 adrenoceptor beta 2 Homo sapiens 158-166 27657826-2 2016 We reported that fenoterol, a beta2-adrenergic receptor (beta2-AR) agonist, inhibited lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells, a monocytic cell line in previous studies. Fenoterol 17-26 adrenoceptor beta 2 Homo sapiens 57-65 27657826-5 2016 In this study, we explored the mechanism of beta2-AR stimulation with fenoterol in AICAR-induced inflammatory cytokine secretion in THP-1 cells. Fenoterol 70-79 adrenoceptor beta 2 Homo sapiens 44-52 25637582-0 2015 Interaction of fenoterol stereoisomers with beta2-adrenoceptor-G salpha fusion proteins: antagonist and agonist competition binding. Fenoterol 15-24 adrenoceptor beta 2 Homo sapiens 44-62 25637582-2 2015 Fenoterol stereoisomers were successfully used to probe ligand-specific activation (functional selectivity) of the beta2-adrenoceptor (beta2AR) (Reinartz et al. Fenoterol 0-9 adrenoceptor beta 2 Homo sapiens 115-133 25637582-2 2015 Fenoterol stereoisomers were successfully used to probe ligand-specific activation (functional selectivity) of the beta2-adrenoceptor (beta2AR) (Reinartz et al. Fenoterol 0-9 adrenoceptor beta 2 Homo sapiens 135-142 25637582-4 2015 In the present study, we extended the pharmacological profile of fenoterol stereoisomers using beta2AR-Gsalpha fusion proteins in agonist and antagonist competition binding assays. Fenoterol 65-74 adrenoceptor beta 2 Homo sapiens 95-102 25342094-0 2015 Structure-bias relationships for fenoterol stereoisomers in six molecular and cellular assays at the beta2-adrenoceptor. Fenoterol 33-42 adrenoceptor beta 2 Homo sapiens 101-119 25342094-8 2015 Ligand bias was calculated using an operational model of agonism and revealed that the fenoterol scaffold constitutes a promising lead structure for the development of Gs-biased beta2AR agonists. Fenoterol 87-96 adrenoceptor beta 2 Homo sapiens 178-185 24615679-4 2014 The method has been successfully tested on the beta2-adrenergic receptor (beta2-AR) binding the four fenoterol stereoisomers by both metadynamics simulations and replica-exchange MD. Fenoterol 101-110 adrenoceptor beta 2 Homo sapiens 47-72 24633512-3 2014 Using His-tagged beta2-adrenoceptor (beta2-AR) as a probe, we developed a new mathematical model to elucidate the interactions between the receptor and five ligands (methoxyphenamine, terbutaline, salbutamol, tulobuterol and fenoterol). Fenoterol 225-234 adrenoceptor beta 2 Homo sapiens 17-35 24633512-3 2014 Using His-tagged beta2-adrenoceptor (beta2-AR) as a probe, we developed a new mathematical model to elucidate the interactions between the receptor and five ligands (methoxyphenamine, terbutaline, salbutamol, tulobuterol and fenoterol). Fenoterol 225-234 adrenoceptor beta 2 Homo sapiens 37-45 24615679-4 2014 The method has been successfully tested on the beta2-adrenergic receptor (beta2-AR) binding the four fenoterol stereoisomers by both metadynamics simulations and replica-exchange MD. Fenoterol 101-110 adrenoceptor beta 2 Homo sapiens 74-82 24326276-0 2014 Comparative molecular field analysis of fenoterol derivatives interacting with an agonist-stabilized form of the beta2-adrenergic receptor. Fenoterol 40-49 adrenoceptor beta 2 Homo sapiens 113-138 24441217-1 2014 Fenoterol and its derivatives are selective beta2-adrenergic receptor (beta2-AR) agonists whose stereoselective biological activities have been extensively investigated in the past decade; a complete stereochemical characterization of fenoterol derivatives is therefore crucial for a better understanding of the effects of stereochemistry on beta2-AR binding. Fenoterol 0-9 adrenoceptor beta 2 Homo sapiens 44-69 24441217-1 2014 Fenoterol and its derivatives are selective beta2-adrenergic receptor (beta2-AR) agonists whose stereoselective biological activities have been extensively investigated in the past decade; a complete stereochemical characterization of fenoterol derivatives is therefore crucial for a better understanding of the effects of stereochemistry on beta2-AR binding. Fenoterol 0-9 adrenoceptor beta 2 Homo sapiens 71-79 24441217-1 2014 Fenoterol and its derivatives are selective beta2-adrenergic receptor (beta2-AR) agonists whose stereoselective biological activities have been extensively investigated in the past decade; a complete stereochemical characterization of fenoterol derivatives is therefore crucial for a better understanding of the effects of stereochemistry on beta2-AR binding. Fenoterol 0-9 adrenoceptor beta 2 Homo sapiens 342-350 24441217-1 2014 Fenoterol and its derivatives are selective beta2-adrenergic receptor (beta2-AR) agonists whose stereoselective biological activities have been extensively investigated in the past decade; a complete stereochemical characterization of fenoterol derivatives is therefore crucial for a better understanding of the effects of stereochemistry on beta2-AR binding. Fenoterol 235-244 adrenoceptor beta 2 Homo sapiens 71-79 24326276-6 2014 The CoMFA model of the agonist-stabilized beta2-AR suggests that the binding of the fenoterol analogs to an agonist-stabilized conformation of the beta2-AR is governed to a greater extend by steric effects than binding to the [(3)H]-CGP-12177-stabilized conformation(s) in which electrostatic interactions play a more predominate role. Fenoterol 84-93 adrenoceptor beta 2 Homo sapiens 42-50 24326276-6 2014 The CoMFA model of the agonist-stabilized beta2-AR suggests that the binding of the fenoterol analogs to an agonist-stabilized conformation of the beta2-AR is governed to a greater extend by steric effects than binding to the [(3)H]-CGP-12177-stabilized conformation(s) in which electrostatic interactions play a more predominate role. Fenoterol 84-93 adrenoceptor beta 2 Homo sapiens 147-155 22760074-1 2012 Fenoterol has been reported to be a potent and selective beta(2)-adrenoceptor agonist and is currently used clinically to treat asthma. Fenoterol 0-9 adrenoceptor beta 2 Homo sapiens 57-77 22776956-1 2012 Inhibition of cell proliferation by fenoterol and fenoterol derivatives in 1321N1 astrocytoma cells is consistent with beta(2)-adrenergic receptor (beta(2)-AR) stimulation. Fenoterol 36-45 adrenoceptor beta 2 Homo sapiens 119-146 22776956-1 2012 Inhibition of cell proliferation by fenoterol and fenoterol derivatives in 1321N1 astrocytoma cells is consistent with beta(2)-adrenergic receptor (beta(2)-AR) stimulation. Fenoterol 36-45 adrenoceptor beta 2 Homo sapiens 148-158 22776956-1 2012 Inhibition of cell proliferation by fenoterol and fenoterol derivatives in 1321N1 astrocytoma cells is consistent with beta(2)-adrenergic receptor (beta(2)-AR) stimulation. Fenoterol 50-59 adrenoceptor beta 2 Homo sapiens 119-146 22776956-1 2012 Inhibition of cell proliferation by fenoterol and fenoterol derivatives in 1321N1 astrocytoma cells is consistent with beta(2)-adrenergic receptor (beta(2)-AR) stimulation. Fenoterol 50-59 adrenoceptor beta 2 Homo sapiens 148-158 24043542-0 2013 Molecular interactions between fenoterol stereoisomers and derivatives and the beta2-adrenergic receptor binding site studied by docking and molecular dynamics simulations. Fenoterol 31-40 adrenoceptor beta 2 Homo sapiens 79-104 24043542-2 2013 In the present study stereoisomers of fenoterol and some of its derivatives (N = 94 molecules) were used as molecular probes to identify differences in stereo-recognition interactions between beta2-AR and structurally similar agonists. Fenoterol 38-47 adrenoceptor beta 2 Homo sapiens 192-200 24043542-3 2013 The present study aimed at determining the 3D molecular models of the fenoterol derivative-beta2-AR complexes. Fenoterol 70-79 adrenoceptor beta 2 Homo sapiens 91-99 24043542-9 2013 Furthermore, the molecular dynamics simulations were used to study the molecular mechanism of interaction between ligands ((R,R")- and (S,S")-fenoterol) and beta2-AR. Fenoterol 135-151 adrenoceptor beta 2 Homo sapiens 157-165 22760074-5 2012 Fenoterol was added cumulatively in the presence of the beta(2)-adrenoceptor antagonist ICI118551 or the beta(3)-adrenoceptor antagonist L-748337. Fenoterol 0-9 adrenoceptor beta 2 Homo sapiens 56-76 20144591-0 2010 The effect of stereochemistry on the thermodynamic characteristics of the binding of fenoterol stereoisomers to the beta(2)-adrenoceptor. Fenoterol 85-94 adrenoceptor beta 2 Homo sapiens 116-136 22434858-6 2012 The beta(2)-AR agonists tested in this study have considerably higher affinity for the agonist conformation of the receptor, and K(i) values determined for fenoterol analogs model much better the cAMP activity of the beta(2)-AR elicited by these ligands. Fenoterol 156-165 adrenoceptor beta 2 Homo sapiens 4-14 22434858-6 2012 The beta(2)-AR agonists tested in this study have considerably higher affinity for the agonist conformation of the receptor, and K(i) values determined for fenoterol analogs model much better the cAMP activity of the beta(2)-AR elicited by these ligands. Fenoterol 156-165 adrenoceptor beta 2 Homo sapiens 217-227 20144591-5 2010 All of the fenoterol stereoisomers are full agonists of the beta(2)-AR, and, therefore, the results of this study are inconsistent with the previously described "thermodynamic agonist-antagonist discrimination", in which the binding of an agonist to the beta-AR is entropy-driven and the binding of an antagonist is enthalpy-driven. Fenoterol 11-20 adrenoceptor beta 2 Homo sapiens 60-70 21365223-7 2011 In case of agonists of beta(2)AR, the (R,R) and (S,S) stereoisomers of fenoterol, the molecular dynamics simulations provided evidence of different binding modes while preserving the same average position of ligands in the binding site. Fenoterol 71-80 adrenoceptor beta 2 Homo sapiens 23-32 21320165-16 2011 Albuterol and fenoterol could suppress poly I:C-induced RANTES and IP-10 expression in human bronchial epithelial cells via at least partly the beta2-adrenoreceptor-cAMP and the MAPK pathways, implicating that albuterol and fenoterol could exert anti-inflammatory effect and benefit asthmatic patients by suppressing RANTES and IP-10 expression. Fenoterol 14-23 adrenoceptor beta 2 Homo sapiens 144-164 20837485-6 2010 A similar partial beta(2)AR activation signal was revealed for the synthetic agonists fenoterol and terbutaline. Fenoterol 86-95 adrenoceptor beta 2 Homo sapiens 18-27 20837485-8 2010 In contrast, fenoterol was quite efficient in triggering beta-arrestin2 recruitment to the cell surface and its interaction with beta(2)AR, as well as internalization of the receptors, whereas norepinephrine caused partial and slow changes in these assays. Fenoterol 13-22 adrenoceptor beta 2 Homo sapiens 129-138 20144591-1 2010 The binding thermodynamics of the stereoisomers of fenoterol, (R,R")-, (S,S")-, (R,S")-, and (S,R")-fenoterol, to the beta(2)-adrenergic receptor (beta(2)-AR) have been determined. Fenoterol 51-60 adrenoceptor beta 2 Homo sapiens 118-145 20144591-1 2010 The binding thermodynamics of the stereoisomers of fenoterol, (R,R")-, (S,S")-, (R,S")-, and (S,R")-fenoterol, to the beta(2)-adrenergic receptor (beta(2)-AR) have been determined. Fenoterol 51-60 adrenoceptor beta 2 Homo sapiens 147-157 19703961-6 2009 In contrast to zinterol, stimulation of I(Ca,L) by fenoterol (fen-beta(2)-AR), a beta(2)-AR agonist that acts exclusively via G(s) signalling, was smaller in +LMN than LMN myocytes. Fenoterol 51-60 adrenoceptor beta 2 Homo sapiens 81-91 20036561-0 2010 Comparative molecular field analysis of fenoterol derivatives: A platform towards highly selective and effective beta(2)-adrenergic receptor agonists. Fenoterol 40-49 adrenoceptor beta 2 Homo sapiens 113-140 19890360-1 2009 AIM: To investigate the molecular mechanism and signaling pathway by which fenoterol, a beta(2)-adrenergic receptor (beta(2)-AR) agonist, produces anti-inflammatory effects. Fenoterol 75-84 adrenoceptor beta 2 Homo sapiens 88-115 19890360-1 2009 AIM: To investigate the molecular mechanism and signaling pathway by which fenoterol, a beta(2)-adrenergic receptor (beta(2)-AR) agonist, produces anti-inflammatory effects. Fenoterol 75-84 adrenoceptor beta 2 Homo sapiens 117-127 19703961-6 2009 In contrast to zinterol, stimulation of I(Ca,L) by fenoterol (fen-beta(2)-AR), a beta(2)-AR agonist that acts exclusively via G(s) signalling, was smaller in +LMN than LMN myocytes. Fenoterol 51-60 adrenoceptor beta 2 Homo sapiens 66-76 16448568-8 2006 Our data support the existence of differences between these six genotypes both in the shape of the dose response relationship of the beta2-adrenoceptor agonist fenoterol as well as in the propensity to develop tolerance for these effects by pre-treatment with terbutaline. Fenoterol 160-169 adrenoceptor beta 2 Homo sapiens 133-151 16917835-1 2006 BACKGROUND: rac-Fenoterol is a beta2-adrenoceptor agonist (beta2-AR) used in the treatment of asthma. Fenoterol 16-25 adrenoceptor beta 2 Homo sapiens 31-49 16917835-1 2006 BACKGROUND: rac-Fenoterol is a beta2-adrenoceptor agonist (beta2-AR) used in the treatment of asthma. Fenoterol 16-25 adrenoceptor beta 2 Homo sapiens 59-67 19462961-1 2009 Phenolic beta(2)-adrenoreceptor agonists salbutamol, fenoterol, and terbutaline relax smooth muscle cells that relieve acute airway bronchospasm associated with asthma. Fenoterol 53-62 adrenoceptor beta 2 Homo sapiens 9-31 18838481-2 2009 Our previous studies have demonstrated that although most beta(2)-adrenoceptor agonists activate both G(s) and G(i) proteins, fenoterol, a full agonist of beta(2)-adrenoceptor, selectively activates G(s) protein. Fenoterol 126-135 adrenoceptor beta 2 Homo sapiens 155-175 18641310-8 2008 In human monocytes, epinephrine and the beta(2) adrenoreceptor agonist fenoterol potently inhibited LPS-induced TNF-alpha and IL-12, but stimulated IL-10 production. Fenoterol 71-80 adrenoceptor beta 2 Homo sapiens 40-62 17506540-0 2007 Comparative molecular field analysis of the binding of the stereoisomers of fenoterol and fenoterol derivatives to the beta2 adrenergic receptor. Fenoterol 76-85 adrenoceptor beta 2 Homo sapiens 119-144 17506540-0 2007 Comparative molecular field analysis of the binding of the stereoisomers of fenoterol and fenoterol derivatives to the beta2 adrenergic receptor. Fenoterol 90-99 adrenoceptor beta 2 Homo sapiens 119-144 17506540-1 2007 Stereoisomers of fenoterol and six fenoterol derivatives have been synthesized and their binding affinities for the beta2 adrenergic receptor (Kibeta2-AR), the subtype selectivity relative to the beta1-AR (Kibeta1-AR/Kibeta2-AR) and their functional activities were determined. Fenoterol 17-26 adrenoceptor beta 2 Homo sapiens 116-141 16917835-12 2006 DISCUSSION: Previous studies have shown that rac-fenoterol acts as an apparent beta2-AR/G(s) selective agonist and fully restores diminished beta2-AR contractile response in cardiomyocytes from failing hearts of spontaneously hypertensive rats (SHR). Fenoterol 49-58 adrenoceptor beta 2 Homo sapiens 79-87 16917835-12 2006 DISCUSSION: Previous studies have shown that rac-fenoterol acts as an apparent beta2-AR/G(s) selective agonist and fully restores diminished beta2-AR contractile response in cardiomyocytes from failing hearts of spontaneously hypertensive rats (SHR). Fenoterol 49-58 adrenoceptor beta 2 Homo sapiens 141-149 15965358-1 2005 We examined whether the beta2-adrenoceptor agonists fenoterol and salbutamol, the beta3-adrenoceptor agonists CL 316243 and ZD 2079, and the agonists of the low-affinity state of beta-adrenoceptors, cyanopindolol and CGP 12177 block alpha1-adrenoceptors in that concentration range in which they relax the human pulmonary and rat mesenteric arteries preconstricted with phenylephrine 10 microM and 1 microM, respectively. Fenoterol 52-61 adrenoceptor beta 2 Homo sapiens 24-42 15351928-1 2004 Chronic exposure to beta(2)-adrenoceptor agonists, especially fenoterol, has been shown to increase smooth muscle contraction to endothelin-1 in human bronchi partly through tachykinin-mediated pathways. Fenoterol 62-71 adrenoceptor beta 2 Homo sapiens 20-40 15728216-13 2005 Intravenous tocolysis with the beta2-adrenergic receptor agonist fenoterol leads to complete desensitization of the beta-adrenergic receptor system. Fenoterol 65-74 adrenoceptor beta 2 Homo sapiens 31-56 15715182-4 2005 Traditional beta2-adrenoceptor agonists (beta2-agonists), such as salbutamol, terbutaline and fenoterol, were characterised by a rapid onset but relatively short duration of action. Fenoterol 94-103 adrenoceptor beta 2 Homo sapiens 12-30 16147906-2 2005 We examined whether the beta2-adrenoceptor agonists, procaterol and fenoterol, induce human Per1 mRNA expression in human bronchial epithelium. Fenoterol 68-77 adrenoceptor beta 2 Homo sapiens 24-42 12154173-2 2002 When isoproterenol (ISO; 0.1 microM) plus the beta(2)-AR antagonist ICI 118,551 (ISO-beta(1)-AR stimulation) or 0.1 microM fenoterol, a beta(2)-AR agonist (FEN-beta(2)-AR stimulation) increased I(Ca,L), ACh (1 microM) inhibited I(Ca,L) by -60 +/- 4 and -63 +/- 6 %, respectively. Fenoterol 123-132 adrenoceptor beta 2 Homo sapiens 136-146 12452831-0 2002 Inhibition by fenoterol of human eosinophil functions including beta2-adrenoceptor-independent actions. Fenoterol 14-23 adrenoceptor beta 2 Homo sapiens 64-82 12154173-2 2002 When isoproterenol (ISO; 0.1 microM) plus the beta(2)-AR antagonist ICI 118,551 (ISO-beta(1)-AR stimulation) or 0.1 microM fenoterol, a beta(2)-AR agonist (FEN-beta(2)-AR stimulation) increased I(Ca,L), ACh (1 microM) inhibited I(Ca,L) by -60 +/- 4 and -63 +/- 6 %, respectively. Fenoterol 123-132 adrenoceptor beta 2 Homo sapiens 136-146 9730867-4 1998 Concanavalin A (Con A)-induced IFN-gamma, GM-CSF, and IL-3 mRNAs are dose-dependently inhibited by the nonselective betaAR agonist isoproterenol and by the selective beta2AR agonist fenoterol. Fenoterol 182-191 adrenoceptor beta 2 Homo sapiens 166-173 11755157-2 2001 In this study, we have assessed the effects of prostaglandin E(2) and the beta(2)-adrenoceptor agonist, fenoterol on RANTES (regulated upon activation, normal T cell expressed and secreted) release by these cells. Fenoterol 104-113 adrenoceptor beta 2 Homo sapiens 74-94 10464825-3 1999 The present study was designed to test in vitro whether fenoterol, a short-acting beta 2-adrenoceptor agonist, could modify human blood neutrophil recruitment and antimicrobial activity. Fenoterol 56-65 adrenoceptor beta 2 Homo sapiens 82-101 9734347-0 1998 Downregulation of the expression of intercellular adhesion molecule (ICAM)-1 on bronchial epithelial cells by fenoterol, a beta2-adrenoceptor agonist. Fenoterol 110-119 adrenoceptor beta 2 Homo sapiens 123-141 9056046-10 1997 beta 2-AR partial agonist activity may also be expressed as antagonism in the presence of an exogenous full agonist, as for example attenuation of fenoterol induced responses by salmeterol. Fenoterol 147-156 adrenoceptor beta 2 Homo sapiens 0-9 9295336-5 1997 The coupling efficiencies for betaAR agonist activation of adenylyl cyclase relative to epinephrine (100%) were 42% for fenoterol, 4.9% for albuterol, 2.5% for dobutamine, and 1.1% for ephedrine. Fenoterol 120-129 adrenoceptor beta 2 Homo sapiens 30-36 9295336-6 1997 At concentrations of these agonists yielding >90% receptor occupancy, the rate and extent (0-30 min) of agonist-induced desensitization of betaAR activation of adenylyl cyclase followed the same order as coupling efficiency, i.e. epinephrine >/= fenoterol > albuterol > dobutamine > ephedrine. Fenoterol 252-261 adrenoceptor beta 2 Homo sapiens 142-148 9295336-9 1997 The two strongest agonists, epinephrine and fenoterol, provoked 11-13-fold increases in the level of betaAR phosphorylation after just 1 min, whereas the weak agonists dobutamine and ephedrine caused only 3-4-fold increases, similar to levels induced by cAMP-dependent protein kinase activation with forskolin. Fenoterol 44-53 adrenoceptor beta 2 Homo sapiens 101-107 9209250-8 1997 CONCLUSIONS: This study shows in a model of controlled, physiologic stimulation of renal erythropoietin production that the beta 2-adrenergic receptor agonist fenoterol but not the beta 1-adrenergic receptor agonist dobutamine is able to increase erythropoietin levels in humans. Fenoterol 159-168 adrenoceptor beta 2 Homo sapiens 124-150 8777955-0 1996 Role of cyclic AMP in the modulation of IgE production by the beta 2-adrenoceptor agonist, fenoterol. Fenoterol 91-100 adrenoceptor beta 2 Homo sapiens 62-81 8730730-13 1996 Of the other commonly used beta 2-adrenoceptor agonists, fenoterol, and formoterol, but not salbutamol, caused moderate inhibition of neutrophil oxidant generation by a superoxide-scavenging mechanism. Fenoterol 57-66 adrenoceptor beta 2 Homo sapiens 27-46 3208783-1 1988 We investigated the effect of Fenoterol, a selective beta 2 adrenoceptor stimulant, on mucociliary clearance in 12 patients with chronic bronchitis. Fenoterol 30-39 adrenoceptor beta 2 Homo sapiens 53-72 8911881-1 1996 OBJECTIVE: To analyse fenoterol-induced tachycardia and hypokalaemia, the most important and most frequent adverse effects of tocolytic therapy with beta 2-adrenoceptor agonists in females of childbearing age. Fenoterol 22-31 adrenoceptor beta 2 Homo sapiens 149-168 1348446-1 1992 1. alpha 1-Adrenoceptor (phenylephrine in the presence of propranolol) and beta 2-adrenoceptor (fenoterol)-mediated positive inotropic effects were investigated in human ventricular preparations isolated from five non-failing (prospective organ donors) and from eight explanted failing hearts with end-stage idiopathic dilative cardiomyopathy (NYHA IV). Fenoterol 96-105 adrenoceptor beta 2 Homo sapiens 75-94 1493852-0 1992 The pharmacokinetics of the beta 2-adrenoceptor agonist fenoterol in healthy women. Fenoterol 56-65 adrenoceptor beta 2 Homo sapiens 28-47 8103795-5 1993 The beta 2 adrenoceptor agonist, fenoterol, produced a dose-dependent increase in operant behavior but colonic temperature fell and thermal balance reflected the characteristic effects of a thermolytic agent. Fenoterol 33-42 adrenoceptor beta 2 Homo sapiens 4-23 8094228-2 1993 In the present report it was shown that beta 2-adrenoceptor agonists, salbutamol and fenoterol, potentiated the IL-4-induced IgE production without significantly affecting the expression of the low affinity receptor for IgE at the cell surface of monocytes and B lymphocytes. Fenoterol 85-94 adrenoceptor beta 2 Homo sapiens 40-59 1682274-3 1991 When a beta 2-adrenoceptor agonist, either salbutamol or fenoterol, was added to U937 cells or monocytes both the IL-4-induced CD23 expression and release were markedly up-regulated. Fenoterol 57-66 adrenoceptor beta 2 Homo sapiens 7-26 6203844-4 1984 Propranolol, a competitive antagonist of beta 2-adrenergic receptor, blocks the inhibition of release and the cAMP accumulation caused by fenoterol. Fenoterol 138-147 adrenoceptor beta 2 Homo sapiens 41-67 2870555-10 1986 Anomalies may exist in the banning of 2 beta 2-adrenoceptor agonists, fenoterol and orciprenaline (metaproterenol). Fenoterol 70-79 adrenoceptor beta 2 Homo sapiens 40-59 3085356-2 1986 A broncho-selective beta 2-adrenoceptor agonist fenoterol was able to prevent the antigen-induced leukotriene release completely, whereas the Ca++-ionophore induced leukotriene release was only moderately inhibited. Fenoterol 48-57 adrenoceptor beta 2 Homo sapiens 20-39 1013850-0 1976 A comparison of the uterine beta2-adrenoreceptor selectivity of fenoterol, hexoprenaline, ritodrine and salbutamol. Fenoterol 64-73 adrenoceptor beta 2 Homo sapiens 28-48 1013850-1 1976 A study was undertaken to compare the uterine beta2-adrenoreceptor selectivity of fenoterol, hexoprenaline, ritodrine and salbutamol. Fenoterol 82-91 adrenoceptor beta 2 Homo sapiens 46-66