PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31609387-0 2020 Acute 4,4"-Methylene Diphenyl Diisocyanate Exposure-Mediated Downregulation of miR-206-3p and miR-381-3p Activates Inducible Nitric Oxide Synthase Transcription by Targeting Calcineurin/NFAT Signaling in Macrophages. 4,4'-diphenylmethane diisocyanate 6-42 microRNA 381 Mus musculus 94-101 31609387-2 2020 Using a nose-only mouse inhalation model, we find that circulating microRNA (miR)-206-3p and miR-381-3p are downregulated after MDI exposure; however, cellular miR-206-3p and miR-381-3p responses after MDI aerosol exposure and their pathophysiological roles in MDI-OA are unknown. 4,4'-diphenylmethane diisocyanate 128-131 microRNA 381 Mus musculus 93-100 31609387-3 2020 We hypothesize that miR-206-3p and miR-381-3p-regulated mechanisms cause increased expression of the inducible nitric oxide synthase (iNOS) after MDI aerosol exposure. 4,4'-diphenylmethane diisocyanate 146-149 microRNA 381 Mus musculus 35-42 31609387-8 2020 Downregulation of miR-206-3p and miR-381-3p following by MDI exposure induces Calcineurin/NFAT signaling-mediated iNOS transcription in macrophages and BALCs. 4,4'-diphenylmethane diisocyanate 57-60 microRNA 381 Mus musculus 33-40