PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31473362-0	2019	Structure-activity relationships of flurbiprofen analogues as stabilizers of the amyloidogenic protein transthyretin.	Flurbiprofen	36-48	transthyretin	Homo sapiens	103-116	
31473362-3	2019	Herein, we report on in vitro, ex vivo, and X-ray analyses to assess the TTR structural stabilization by analogues of flurbiprofen, a non-steroidal anti-inflammatory drug (NSAID).	Flurbiprofen	118-130	transthyretin	Homo sapiens	73-76	
31473362-4	2019	Overall, considering together binding selectivity and protective effects on TTR native structure by flurbiprofen analogues in the presence of plasma proteins, as determined by Western Blot,the aforementioned properties of analyzed compounds appear to be better (CHF5075 and CHF4802) or similar (CHF4795) or worse (CHF5074, also known as CSP-1103) as compared to those of diflunisal, used as a reference TTR stabilizer.	Flurbiprofen	100-112	transthyretin	Homo sapiens	76-79	
31473362-6	2019	Distinct interactions with TTR appear to characterize flurbiprofen analogues and the NSAID diflunisal and its analogues as TTR stabilizers.	Flurbiprofen	54-66	transthyretin	Homo sapiens	27-30	
31473362-7	2019	Relationships between stabilizing effect on TTR by flurbiprofen analogues determined experimentally and molecular details of their interactions with TTR have been established, providing the rationale for their protective effects on the native protein structure.	Flurbiprofen	51-63	transthyretin	Homo sapiens	44-47	
31473362-7	2019	Relationships between stabilizing effect on TTR by flurbiprofen analogues determined experimentally and molecular details of their interactions with TTR have been established, providing the rationale for their protective effects on the native protein structure.	Flurbiprofen	51-63	transthyretin	Homo sapiens	149-152