PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26566264-7	2016	E2 and T significantly reduced secretion of BDNF; effects prevented by estrogen and androgen receptor inhibitor, ICI 182,780 (1 muM), and flutamide (10 muM), respectively.	Flutamide	138-147	latexin	Homo sapiens	152-155	
23869618-7	2013	These responses were blocked by the androgen receptor antagonist, flutamide (10 muM); the sarcoplasmic reticulum ATPase pump inhibitor, thapsigargin (1 muM); the inositol trisphosphate receptor inhibitor, 2-aminoethyldiphenyl borate (50 muM) and the PLC inhibitor, U-73122 (1 muM).	Flutamide	66-75	latexin	Homo sapiens	80-83	
21876548-7	2012	Addition of the androgen receptor antagonist Flutamide (1 muM) to the media reversed the negative effect of testosterone and DHT by returning AMPK phosphorylation levels to those of basal.	Flutamide	45-54	latexin	Homo sapiens	58-61	
22446520-8	2012	In the inhibition assay, the flutamide hydrolase activities at a flutamide concentration of 5 muM in human liver and jejunum microsomes were strongly inhibited by a selective CES2 inhibitor, 10 muM loperamide, with the residual activities of 22.9 +- 3.5 and 18.6 +- 0.7%, respectively.	Flutamide	29-38	latexin	Homo sapiens	94-97	
22446520-8	2012	In the inhibition assay, the flutamide hydrolase activities at a flutamide concentration of 5 muM in human liver and jejunum microsomes were strongly inhibited by a selective CES2 inhibitor, 10 muM loperamide, with the residual activities of 22.9 +- 3.5 and 18.6 +- 0.7%, respectively.	Flutamide	29-38	latexin	Homo sapiens	194-197	
22446520-11	2012	The relative contribution of CES2 was approximately 75 to 99% at the concentration of 5 muM flutamide.	Flutamide	92-101	latexin	Homo sapiens	88-91	
21111724-11	2011	Flutamide (10 muM), unexpectedly, also strongly increased nuclear beta-catenin accumulation.	Flutamide	0-9	latexin	Homo sapiens	14-17