PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12831835-8	2003	treatment of adult males with flutamide caused an increase in the levels of expression of hCYP1B1 in the adult females, as indicated by the antiandrogenic activity.	Flutamide	30-39	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	90-97	
11160641-5	2001	Four agents were competitive inhibitors of CYP1B1 activity: flutamide (K(i) = 1.0 microM), paclitaxel (K(i) = 31.6 microM), mitoxantrone (K(i) = 11.6 microM), and docetaxel (K(i) = 28.0 microM).	Flutamide	60-69	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	43-49	
11160641-9	2001	Comparison of kinetic parameters (K(m), K(i), V(max)) for flutamide 2-hydroxylation by CYP1B1, CYP1A1, and CYP1A2 indicate that CYP1B1 could play a major role for flutamide biotransformation in tumors.	Flutamide	58-67	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	87-93	
11160641-9	2001	Comparison of kinetic parameters (K(m), K(i), V(max)) for flutamide 2-hydroxylation by CYP1B1, CYP1A1, and CYP1A2 indicate that CYP1B1 could play a major role for flutamide biotransformation in tumors.	Flutamide	58-67	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	128-134	
11160641-9	2001	Comparison of kinetic parameters (K(m), K(i), V(max)) for flutamide 2-hydroxylation by CYP1B1, CYP1A1, and CYP1A2 indicate that CYP1B1 could play a major role for flutamide biotransformation in tumors.	Flutamide	163-172	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	87-93	
11160641-9	2001	Comparison of kinetic parameters (K(m), K(i), V(max)) for flutamide 2-hydroxylation by CYP1B1, CYP1A1, and CYP1A2 indicate that CYP1B1 could play a major role for flutamide biotransformation in tumors.	Flutamide	163-172	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	128-134