PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9049038-4	1997	Ornithine decarboxylase (ODC) activity was significantly decreased by flutamide, and to a lesser extent by casodex.	Flutamide	70-79	ornithine decarboxylase 1	Rattus norvegicus	0-23	
9049038-4	1997	Ornithine decarboxylase (ODC) activity was significantly decreased by flutamide, and to a lesser extent by casodex.	Flutamide	70-79	ornithine decarboxylase 1	Rattus norvegicus	25-28	
3397935-5	1988	ODC activity was significantly decreased by flutamide treatment of intact rats, but even at the highest dose used (10 mg/day) only a 39% inhibition was observed.	Flutamide	44-53	ornithine decarboxylase 1	Rattus norvegicus	0-3	
3397935-7	1988	In androgen-treated castrated rats, flutamide caused epididymal ODC to fall to undetectable values.	Flutamide	36-45	ornithine decarboxylase 1	Rattus norvegicus	64-67	
3397935-8	1988	These results show that: (1) androgens are essential for the maintenance of ODC activity in the epididymis; (2) epididymal ODC activity is maximally stimulated by endogenous androgens, at least in the pubertal rat; (3) the apparent potency of flutamide is substantially lowered by an increase in epididymal androgens.	Flutamide	243-252	ornithine decarboxylase 1	Rattus norvegicus	123-126