PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11748459-3	2002	The microarray showed that the most strongly up-regulated gene by 5-FU was vitamin D3 up-regulated protein 1 (VDUP1), an interesting stress response gene, which was originally reported as a vitamin D3 inducible gene in HL-60.	Cholecalciferol	75-85	thioredoxin interacting protein	Homo sapiens	110-115	
24451003-0	2014	Effects of vitamin D3 stimulation of thioredoxin-interacting protein in hepatocellular carcinoma.	Cholecalciferol	11-21	thioredoxin interacting protein	Homo sapiens	37-68	
24451003-4	2014	In addition, we wanted to determine the effects of vitamin D3-induced TXNIP stimulation in HCC-derived cell lines.	Cholecalciferol	51-61	thioredoxin interacting protein	Homo sapiens	70-75	
24451003-8	2014	RESULTS: TXNIP expression levels were low in HCC cell lines, and vitamin D3 stimulated TXNIP expression in vitro.	Cholecalciferol	65-75	thioredoxin interacting protein	Homo sapiens	87-92	
24451003-9	2014	In HCC cells transfected with a TXNIP expression vector or treated with exogenous vitamin D3, there was a reduction in cell proliferation and an increase in apoptosis.	Cholecalciferol	82-92	thioredoxin interacting protein	Homo sapiens	32-37	
24451003-13	2014	Vitamin D3 stimulates TXNIP expression, resulting in diminished proliferation and enhanced apoptosis.	Cholecalciferol	0-10	thioredoxin interacting protein	Homo sapiens	22-27	
24451003-15	2014	These findings suggest that stimulation of TXNIP expression, by factors such as vitamin D3, may attenuate carcinogenesis in patients with chronic liver disease.	Cholecalciferol	80-90	thioredoxin interacting protein	Homo sapiens	43-48	
21964212-1	2011	TXNIP (also named as VDUP-1 or TBP-2) was originally isolated in HL60 cells treated with Vitamin D3.	Cholecalciferol	89-99	thioredoxin interacting protein	Homo sapiens	0-5	
21964212-1	2011	TXNIP (also named as VDUP-1 or TBP-2) was originally isolated in HL60 cells treated with Vitamin D3.	Cholecalciferol	89-99	thioredoxin interacting protein	Homo sapiens	21-27	
31519581-6	2019	CONCLUSION: Antioxidant regulation via TXNIP is an important cell death mechanism in human endometrial cancer, and occurs via induction by vitamin D3.	Cholecalciferol	139-149	thioredoxin interacting protein	Homo sapiens	39-44	
29534438-0	2018	Expression of TXNIP in Cancer Cells and Regulation by 1,25(OH)2D3: Is It Really the Vitamin D3 Upregulated Protein?	Cholecalciferol	84-94	thioredoxin interacting protein	Homo sapiens	14-19	
29682582-0	2018	Vitamin D3 Protects against Diabetic Retinopathy by Inhibiting High-Glucose-Induced Activation of the ROS/TXNIP/NLRP3 Inflammasome Pathway.	Cholecalciferol	0-10	thioredoxin interacting protein	Homo sapiens	106-111	
29682582-7	2018	Results: Vitamin D3 significantly downregulated intracellular ROS and inhibited TRX-interacting protein (TXNIP)/NOD-like receptor family, pyrin domain-containing 3 (NLRP3) inflammasome pathway activation.	Cholecalciferol	9-19	thioredoxin interacting protein	Homo sapiens	80-103	
29682582-7	2018	Results: Vitamin D3 significantly downregulated intracellular ROS and inhibited TRX-interacting protein (TXNIP)/NOD-like receptor family, pyrin domain-containing 3 (NLRP3) inflammasome pathway activation.	Cholecalciferol	9-19	thioredoxin interacting protein	Homo sapiens	105-110	
29682582-10	2018	Conclusions: Vitamin D3 decreases diabetes-induced ROS and exerts protective effects against retinal vascular damage and cell apoptosis in association with inhibition of the ROS/TXNIP/NLRP3 inflammasome pathway.	Cholecalciferol	13-23	thioredoxin interacting protein	Homo sapiens	178-183