PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33548240-2	2021	Meanwhile, AMPD promotes the formation of substrates of xanthine oxidoreductase (XOR), which produces ROS as a byproduct.	ros	102-105	xanthine dehydrogenase	Rattus norvegicus	56-79	
33548240-2	2021	Meanwhile, AMPD promotes the formation of substrates of xanthine oxidoreductase (XOR), which produces ROS as a byproduct.	ros	102-105	xanthine dehydrogenase	Rattus norvegicus	81-84	
33548240-10	2021	Inhibition of XOR suppressed the production of tissue ROS and mitochondrial dysfunction and improved ventricular function under the condition of pressure overload in OLETF.	ros	54-57	xanthine dehydrogenase	Rattus norvegicus	14-17	
33548240-11	2021	CONCLUSIONS: The results suggest that increases in the activity of XOR and the formation of XOR substrates by upregulated AMPD contribute to ROS-mediated diastolic ventricular dysfunction at the time of increased cardiac workload in diabetic hearts.	ros	141-144	xanthine dehydrogenase	Rattus norvegicus	67-70	
33548240-11	2021	CONCLUSIONS: The results suggest that increases in the activity of XOR and the formation of XOR substrates by upregulated AMPD contribute to ROS-mediated diastolic ventricular dysfunction at the time of increased cardiac workload in diabetic hearts.	ros	141-144	xanthine dehydrogenase	Rattus norvegicus	92-95	
33132325-1	2020	Xanthine and hypoxanthine are intermediate metabolites of uric acid and a source of reactive oxidative species (ROS) by xanthine oxidoreductase (XOR), suggesting that facilitating their elimination is beneficial.	ros	112-115	xanthine dehydrogenase	Rattus norvegicus	145-148	
33132325-10	2020	Accordingly, it is expected that treatment with XOR and URAT1 inhibitors will effectively decrease purine pools in the body and prevent cell injury due to ROS generated during XOR-mediated reactions.	ros	155-158	xanthine dehydrogenase	Rattus norvegicus	48-51	
33132325-10	2020	Accordingly, it is expected that treatment with XOR and URAT1 inhibitors will effectively decrease purine pools in the body and prevent cell injury due to ROS generated during XOR-mediated reactions.	ros	155-158	xanthine dehydrogenase	Rattus norvegicus	176-179