PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34045966-4	2021	Meanwhile, CD13 can activate NRF1 and up-regulate ROS scavenging genes transcription, such as SOD1, GPX1, GPX2 and GPX3, leading to down-regulation of intracellular ROS level and reducing the sensitivity of cells to chemotherapy agent.	ros	50-53	glutathione peroxidase 1	Homo sapiens	100-104	
21852236-4	2011	Suppression of GPx-1 enhanced TNF-alpha-induced ROS production and ICAM-1 expression, whereas overexpression of GPx-1 attenuated these TNF-alpha-mediated responses.	ros	48-51	glutathione peroxidase 1	Homo sapiens	15-20	
30538220-6	2018	GPx1 degradation caused by glucose deprivation led to further ROS-dependent autophagy activation.	ros	62-65	glutathione peroxidase 1	Homo sapiens	0-4	
22951908-8	2012	GPx1 deficiency led to an accumulation of ROS/RNS and subsequent death of GBM cells after induction of oxidative stress.	ros	42-45	glutathione peroxidase 1	Homo sapiens	0-4	
21852236-7	2011	To analyze further signaling pathways involved in GPx-1-mediated protection from TNF-alpha-induced ROS, we performed microarray analysis of human microvascular endothelial cells treated with TNF-alpha in the presence and absence of GPx-1.	ros	99-102	glutathione peroxidase 1	Homo sapiens	50-55	
34148735-8	2021	Notably, Iberin induced down-regulation of glutathione peroxidase-1 (GPX1), and over-expression of GPX1 reversed Iberin-mediated alterations in the proliferation, apoptosis and ROS accumulation of OC cells.	ros	177-180	glutathione peroxidase 1	Homo sapiens	99-103