PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 3133241-6 1988 The structures of the gangliosides, each identified by means of permethylation anaylsis and enzyme treatment after isolation with antibody monitoring, were shown to be IV6NeuAcnLc4Cer for the former and IV3NeuAcLc4Cer for the latter, indicating that the lacto-series type 2 (nLc4Cer) and 1 (Lc4Cer) chains are sialylated at different linkages, alpha 2-6 and alpha 2-3, respectively. Gangliosides 22-34 immunoglobulin binding protein 1 Homo sapiens 344-353 7952130-3 1994 Furthermore, base-line separation of alpha 2-3 and alpha 2-6 sialylated neolacto-series gangliosides e.g. IV3Neu5Ac-nLcOse4Cer and IV6Neu5Ac-nLcOse4Cer, isolated from human granulocytes, was achieved and pure fractions of each ganglioside were obtained. Gangliosides 88-99 immunoglobulin binding protein 1 Homo sapiens 51-60 8318834-5 1993 Neuraminidase treatment of gangliosides with alpha 2-3 substituted sialic acid is necessary prior to immunostaining whereas alpha 2-6 sialylated gangliosides can be detected without enzyme treatment. Gangliosides 145-157 immunoglobulin binding protein 1 Homo sapiens 124-133 6424662-1 1984 Competition and thermal inactivation experiments with different potential natural substrates indicated that in homogenates of human fibroblasts one single enzyme is acting on both (alpha 2-3) and (alpha 2-6) sialosyl linkages of oligosaccharides and glycoproteins, but not of the ganglioside GM3. Gangliosides 280-291 immunoglobulin binding protein 1 Homo sapiens 197-206 19361287-2 2009 A highly efficient separation of alpha2-3- and alpha2-6-sialylated ganglioside species of different carbohydrate chain length was achieved on an HILIC-amido column, followed by sensitive flow-through ESI-QTOF-MS detection and unambiguous structural identification by tandem MS experiments. Gangliosides 67-78 immunoglobulin binding protein 1 Homo sapiens 47-55 15289269-1 2004 Anti-disialoside antibodies (Abs) that bind NeuAc(alpha2-8) NeuAc epitopes on GQ1b and related gangliosides are found in human autoimmune neuropathy sera and are considered to be pathogenic. Gangliosides 95-107 immunoglobulin binding protein 1 Homo sapiens 50-58 18642128-3 2009 In this study, we have molecularly cloned from zebrafish sources, the orthologues of the six human alpha2,8-sialyltransferases (ST8Sia), a family of sialyltransferases implicated in the alpha2-8-mono-, oligo-, and poly-sialylation of glycoproteins and gangliosides and we have analysed their expression pattern in the embryonic zebrafish nervous system, using in situ hybridization. Gangliosides 252-264 immunoglobulin binding protein 1 Homo sapiens 186-194 14588011-3 2003 A clear-cut series of fragment ions for both types of isomeric gangliosides, carrying alpha2-3- and alpha2-6-linked neuraminic acid, respectively, was obtained by low-energy CID. Gangliosides 63-75 immunoglobulin binding protein 1 Homo sapiens 100-108 12145189-8 2002 Quantification of the predominant receptor ganglioside IV(6)Neu5Ac-nLc4Cer by means of a specific anti-Neu5Acalpha2-6Galbeta1-4GlcNAc-R antibody revealed 3.68 x 10(6) and 1.54 x 10(6) receptor molecules per HL-60 and 5637 cell, respectively; CHO-K1 cells were negative, lacking alpha2-6-sialylated gangliosides. Gangliosides 43-54 immunoglobulin binding protein 1 Homo sapiens 109-117