PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28082351-5	2017	In agreement with this finding, FTY720 pretreatment of human NPC1 mutant fibroblasts restored transport of the cholera toxin B subunit, which binds ganglioside GM1, to the Golgi apparatus.	Gangliosides	148-159	NPC intracellular cholesterol transporter 1	Homo sapiens	61-65	
18681838-1	2009	BACKGROUND INFORMATION: Within the group of lysosomal storage diseases, NPC1 [NPC (Niemann-Pick type C) 1] disease is a lipidosis characterized by excessive accumulation of free cholesterol as well as gangliosides, glycosphingolipids and fatty acids in the late E/L (endosomal/lysosomal) system (Chen et al., 2005) due to a defect in late endosome lipid egress.	Gangliosides	201-213	NPC intracellular cholesterol transporter 1	Homo sapiens	72-76	
27923633-2	2017	On the cellular level NPC1 mutations lead to an accumulation of cholesterol and gangliosides.	Gangliosides	80-92	NPC intracellular cholesterol transporter 1	Homo sapiens	22-26	
26984608-1	2016	Niemann-Pick disease type C (NP-C) is a fatal progressive neurolipidosis involving neuronal storage of cholesterol and gangliosides.	Gangliosides	119-131	NPC intracellular cholesterol transporter 1	Homo sapiens	0-27	
26984608-1	2016	Niemann-Pick disease type C (NP-C) is a fatal progressive neurolipidosis involving neuronal storage of cholesterol and gangliosides.	Gangliosides	119-131	NPC intracellular cholesterol transporter 1	Homo sapiens	29-33	
23433359-1	2013	BACKGROUND: Niemann Pick C (NPC) disease is a neurovisceral lysosomal storage disorder due to mutations in NPC1 or NPC2 genes, characterized by the accumulation of endocytosed unesterified cholesterol, gangliosides and other lipids within the lysosomes/late endosomes.	Gangliosides	202-214	NPC intracellular cholesterol transporter 1	Homo sapiens	107-111	
20525256-9	2010	NP-C is currently described as a cellular cholesterol trafficking defect but in the brain, the prominently stored lipids are gangliosides.	Gangliosides	125-137	NPC intracellular cholesterol transporter 1	Homo sapiens	0-4	
16797010-1	2006	Niemann-Pick C (NPC) disease is a progressive neurological disorder in which cholesterol, gangliosides and bis-monoacylglycerol phosphate accumulate in late endosomes/lysosomes.	Gangliosides	90-102	NPC intracellular cholesterol transporter 1	Homo sapiens	0-14	
16797010-1	2006	Niemann-Pick C (NPC) disease is a progressive neurological disorder in which cholesterol, gangliosides and bis-monoacylglycerol phosphate accumulate in late endosomes/lysosomes.	Gangliosides	90-102	NPC intracellular cholesterol transporter 1	Homo sapiens	16-19	
15632139-1	2005	Niemann-Pick type C (NPC) is an autosomal recessive lipid storage disorder characterized by lysosomal accumulation of cholesterol and gangliosides resulting from a defect in intracellular lipid trafficking.	Gangliosides	134-146	NPC intracellular cholesterol transporter 1	Homo sapiens	0-19	
15632139-1	2005	Niemann-Pick type C (NPC) is an autosomal recessive lipid storage disorder characterized by lysosomal accumulation of cholesterol and gangliosides resulting from a defect in intracellular lipid trafficking.	Gangliosides	134-146	NPC intracellular cholesterol transporter 1	Homo sapiens	21-24	
11202175-7	2001	These studies suggest that the homeostatic regulation of gangliosides and cholesterol in neurons is mediated by NPC1 and that perturbations in this mechanism cause a complex neuronal storage disorder.	Gangliosides	57-69	NPC intracellular cholesterol transporter 1	Homo sapiens	112-116	
15666818-8	2004	Mutations in the npc1 gene results in lysosomal accumulation of cholesterol and gangliosides in humans and in the mouse, which also recapitulates the onset of neurological deficits, neuronal loss and death typical of the most severe form of the human disease.	Gangliosides	80-92	NPC intracellular cholesterol transporter 1	Homo sapiens	17-21	
15666818-10	2004	ALLO treatment was highly effective; ALLO-treated NP-C mice had substantially increased survival and delays in neurologic impairments, coinciding with marked improvements in neuronal survival, and reduction of gangliosides.	Gangliosides	210-222	NPC intracellular cholesterol transporter 1	Homo sapiens	50-54