PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32297127-6 2020 A short treatment course of a pharmacologic agent hypothesized to act as an IRT, such as Cladribine Tablets 3.5 mg/kg or alemtuzumab, can provide long-term suppression of MS disease activity, without need for continuous treatment (the anti-CD20 mechanism of ocrelizumab has the potential to act as an IRT, but is administered continuously, at 6-monthly intervals). Cladribine 89-99 keratin 20 Homo sapiens 240-244 10970137-0 2000 Bone marrow remission of hairy cell leukaemia induced by rituximab (anti-CD20 monoclonal antibody) in a patient refractory to cladribine. Cladribine 126-136 keratin 20 Homo sapiens 73-77 32645640-2 2020 Based on potential similar memory B cell depletion mechanisms with cladribine and alemtuzumab, we hypothesised that CD20-depletion of B cells by ocrelizumab may exhibit a duration of response exceeding the current licenced treatment interval. Cladribine 67-77 keratin 20 Homo sapiens 116-120 22712014-0 2012 Two Cases of Cerebral Involvement in Malignant Lymphoma (CD20+) That Responded to Combination Therapy with Rituximab and Cladribine. Cladribine 121-131 keratin 20 Homo sapiens 57-61